ArticleFrontiers in systems neuroscience2017
Changes in Alpha Frequency and Power of the Electroencephalogram during Volatile-Based General Anesthesia.
Article in Frontiers in systems neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 56 citations in OpenAlex.
- An experimental study of the effect of neuromuscular blockade on EEG-based measures of awareness.Scientific reports · 2026Article
- Characteristics of electroencephalographic changes induced by different hypnotics in elderly patients: a narrative review.Korean journal of anesthesiology · 2026Review
- Xenon anaesthesia is associated with a reduction in frontal electroencephalogram peak alpha frequency.BJA open · 2024Article
- Decrease of the peak heights of EEG bicoherence indicated insufficiency of analgesia during surgery under general anesthesia.Journal of anesthesia · 2024Article
- Cognitive function mediates the relationship between age and anaesthesia-induced oscillatory-specific alpha power.Brain communications · 2024Article
- The medial septum controls hippocampal supra-theta oscillations.Nature communications · 2023Article
- A Real-Time Neurophysiologic Stress Test for the Aging Brain: Novel Perioperative and ICU Applications of EEG in Older Surgical Patients.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023Review
- Quantitative relationship between anteriorization of alpha oscillations and level of general anesthesia.Journal of clinical monitoring and computing · 2023Article
- EEG responses to standardised noxious stimulation during clinical anaesthesia: a pilot study.BJA open · 2023Article
- Spectral EEG correlations from the different phases of general anesthesia.Frontiers in medicine · 2023Article
- [The quantitative EEG in electroencephalogram-based brain monitoring during general anesthesia].Der Anaesthesist · 2021Article
- Continuing professional development module : An updated introduction to electroencephalogram-based brain monitoring during intended general anesthesia.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2020Article
- Low Frontal Alpha Power Is Associated With the Propensity for Burst Suppression: An Electroencephalogram Phenotype for a "Vulnerable Brain".Anesthesia and analgesia · 2020Article
- Association of Sleep Electroencephalography-Based Brain Age Index With Dementia.JAMA network open · 2020Article
- Spectral and Entropic Features Are Altered by Age in the Electroencephalogram in Patients under Sevoflurane Anesthesia.Anesthesiology · 2020Article
- The effect of sevoflurane and isoflurane anesthesia on single unit and local field potentials.Experimental brain research · 2019Article
- Analyzing Electroencephalography (EEG) Waves Provides a Reliable Tool to Assess the Depth of Sevoflurane Anesthesia in Pediatric Patients.Medical science monitor : international medical journal of experimental and clinical research · 2019Article
- Article
- The Human Default Consciousness and Its Disruption: Insights From an EEG Study of Buddhist Jhāna Meditation.Frontiers in human neuroscience · 2019Article
- Cognitive Impairment Is Associated with Absolute Intraoperative Frontal α-Band Power but Not with Baseline α-Band Power: A Pilot Study.Dementia and geriatric cognitive disorders · 2019Observational
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
Oscillations in the electroencephalogram (EEG) at the alpha frequency (8-12 Hz) are thought to be ubiquitous during surgical anesthesia, but the details of how this oscillation responds to ongoing changes in volatile anesthetic concentration have not been well characterized. It is not known how often alpha oscillations are absent in the clinical context, how sensitively alpha frequency and power respond to changes in anesthetic concentration, and what effect increased age has on alpha frequency. Bipolar EEG was recorded frontally from 305 patients undergoing surgery with sevoflurane or desflurane providing general anesthesia. A new method of detecting the presence of alpha oscillations based on the stability of the rate of change of the peak frequency in the alpha range was developed. Linear concentration-response curves were fitted to assess the sensitivity of alpha power and frequency measures to changing levels of anesthesia. Alpha oscillations were seen to be inexplicably absent in around 4% of patients. Maximal alpha power increased with increasing volatile anesthetic concentrations in half of the patients, and decreased in the remaining patients. Alpha frequency decreased with increasing anesthetic concentrations in near to 90% of patients. Increasing age was associated with decreased sensitivity to volatile anesthesia concentrations, and with decreased alpha frequency, which sometimes transitioned into the theta range (5-7 Hz). While peak alpha frequency shows a consistent slowing to increasing volatile concentrations, the peak power of the oscillation does not, suggesting that frequency might be more informative of depth of anesthesia than traditional power based measures during volatile-based anesthesia. The alpha oscillation becomes slower with increasing age, even when the decreased anesthetic needs of older patients were taken into account.
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