Evidence map›Paper›PMID 28611512›Full record

ReviewWorld journal of gastroenterology2017

Hepatitis A virus infection and hepatitis A vaccination in human immunodeficiency virus-positive patients: A review.

Kuan-Yin Lin, Guan-Jhou Chen, Yu-Lin Lee, Yi-Chia Huang, Aristine Cheng, Hsin-Yun Sun, Sui-Yuan Chang, Chun-Eng Liu, Chien-Ching Hung

Open access · greenAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 2 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 2 syntheses or guidelines pooled it, 105 citations in OpenAlex.

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  13. [Expert recommendations on hepatitis A vaccination for adults].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Kuan-Yin LinKuan-Yin Lin, Department of Medicine, National Taiwan University Hospital Jin-Shan Branch, New Taipei 20844, Taiwan.
Guan-Jhou ChenKuan-Yin Lin, Department of Medicine, National Taiwan University Hospital Jin-Shan Branch, New Taipei 20844, Taiwan.
Yu-Lin LeeKuan-Yin Lin, Department of Medicine, National Taiwan University Hospital Jin-Shan Branch, New Taipei 20844, Taiwan.
Yi-Chia HuangKuan-Yin Lin, Department of Medicine, National Taiwan University Hospital Jin-Shan Branch, New Taipei 20844, Taiwan.
Aristine ChengKuan-Yin Lin, Department of Medicine, National Taiwan University Hospital Jin-Shan Branch, New Taipei 20844, Taiwan.
Hsin-Yun SunKuan-Yin Lin, Department of Medicine, National Taiwan University Hospital Jin-Shan Branch, New Taipei 20844, Taiwan.
Sui-Yuan ChangKuan-Yin Lin, Department of Medicine, National Taiwan University Hospital Jin-Shan Branch, New Taipei 20844, Taiwan.
Chun-Eng LiuKuan-Yin Lin, Department of Medicine, National Taiwan University Hospital Jin-Shan Branch, New Taipei 20844, Taiwan.
Chien-Ching HungKuan-Yin Lin, Department of Medicine, National Taiwan University Hospital Jin-Shan Branch, New Taipei 20844, Taiwan.
National Taiwan University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis A virus (HAV) is one of the most common infectious etiologies of acute hepatitis worldwide. The virus is known to be transmitted fecal-orally, resulting in symptoms ranging from asymptomatic infection to fulminant hepatitis. HAV can also be transmitted through oral-anal sex. Residents from regions of low endemicity for HAV infection often remain susceptible in their adulthood. Therefore, clustered HAV infections or outbreaks of acute hepatitis A among men who have sex with men and injecting drug users have been reported in countries of low endemicity for HAV infection. The duration of HAV viremia and stool shedding of HAV may be longer in human immunodeficiency virus (HIV)-positive individuals compared to HIV-negative individuals with acute hepatitis A. Current guidelines recommend HAV vaccination for individuals with increased risks of exposure to HAV (such as from injecting drug use, oral-anal sex, travel to or residence in endemic areas, frequent clotting factor or blood transfusions) or with increased risks of fulminant disease (such as those with chronic hepatitis). The seroconversion rates following the recommended standard adult dosing schedule (2 doses of HAVRIX 1440 U or VAQTA 50 U administered 6-12 mo apart) are lower among HIV-positive individuals compared to HIV-negative individuals. While the response rates may be augmented by adding a booster dose at week 4 sandwiched between the first dose and the 6-mo dose, the need of booster vaccination remain less clear among HIV-positive individuals who have lost anti-HAV antibodies.

Indexed as

AdultComorbidityDisease OutbreaksFemaleHepatitis AHepatitis A AntibodiesHepatitis A VaccinesHepatitis A virusHIV InfectionsHIV SeropositivityHomosexuality, MaleHumansImmunization ProgramsImmunization, SecondaryImmunosuppressive AgentsMaleHepatitis A AntibodiesHepatitis A VaccinesImmunosuppressive AgentsAcute hepatitisEpidemiologyFecal-oral transmissionImmunizationImmunosuppressionInjecting drug useMen who have sex with menOral-anal sexViral hepatitis

Identifiers

PMID28611512
PMCPMC5449416
OpenAlexW2618201747

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.