ArticleScientific reports2017
Phytohormonal crosstalk modulates the expression of miR166/165s, target Class III HD-ZIPs, and KANADI genes during root growth in Arabidopsis thaliana.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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38 citing papers in PubMed, 120 citations in OpenAlex.
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- Exploring the drought-responsive miRNAs and their corresponding target genes in chickpea root tissue.Plant molecular biology · 2025Article
- Genome-Wide Transcriptional Response of Avocado toPlants (Basel, Switzerland) · 2024Article
- Source leaves are regulated by sink strengths through non-coding RNAs and alternative polyadenylation in cucumber (Cucumis sativus L.).BMC plant biology · 2024Article
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- Association between Reactive Oxygen Species, Transcription Factors, and Candidate Genes in Drought-Resistant Sorghum.International journal of molecular sciences · 2024Review
- Characterization of VvmiR166s-Target Modules and Their Interaction Pathways in Modulation of Gibberellic-Acid-Induced Grape Seedless Berries.International journal of molecular sciences · 2023Article
- miRNA mediated regulation of nitrogen response and nitrogen use efficiency of plants: the case of wheat.Physiology and molecular biology of plants : an international journal of functional plant biology · 2023Article
- The miR166d/International journal of molecular sciences · 2023Article
- Genome-wide identification, bioinformatics and expression analysis of HD-Zip gene family in peach.BMC plant biology · 2023Article
- Genome-wide identification and characterization of the HD-Zip gene family and expression analysis in response to stress inPlant signaling & behavior · 2022Article
- Mining the Roles of Cucumber DUF966 Genes in Fruit Development and Stress Response.Plants (Basel, Switzerland) · 2022Article
- Characteristics of microRNAs and Target Genes in Maize Root under Drought Stress.International journal of molecular sciences · 2022Article
- Salicylic Acid in Root Growth and Development.International journal of molecular sciences · 2022Review
- Identification and profiling of conserved microRNAs in different developmental stages of crown imperial (Fritillaria imperialis L.) using high-throughput sequencing.Molecular biology reports · 2022Article
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10 authors at 1 institution in 1 country.
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Abstract
Both phytohormones and non-coding microRNAs (miRNAs) play important role in root development in Arabidopsis thaliana. Mature miR166/165 s, which are derived from precursor transcripts of concerned genes, regulate developmental processes, including leaf and root patterning, by targeting Class III HOMEODOMAIN LEUCINE-ZIPPER (HD-ZIP III) transcription factors (TFs). However, their regulation through hormones remained poorly understood. Here, we show that several phytohormones dynamically regulate the spatio-temporal expression pattern of miR166/165 and target HD-ZIP IIIs in developing roots. Hormone signaling pathway mutants show differential expression pattern of miR166/165, providing further genetic evidence for multilayered regulation of these genes through phytohormones. We further show that a crosstalk of at least six different phytohormones regulate the miR166/165, their target HD-ZIP IIIs, and KANADI (KANs). Our results suggest that HD-ZIP IIIs mediated root development is modulated both transcriptionally through phytohormones and KANs, and post-transcriptionally by miR166/165 that in turn are also regulated by the phytohormonal crosstalk.
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