ArticleInternational journal of obesity (2005)2017
Identification of the ectoenzyme CD38 as a marker of committed preadipocytes.
Article in International journal of obesity (2005), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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Who cites it
8 citing papers in PubMed, 15 citations in OpenAlex.
- Bone Marrow Adipocytes in Multiple Myeloma: Emerging Immunometabolic Interactions and Implications for Immunotherapy.Cancers · 2026Review
- Immunoregulation in cancer-associated cachexia.Journal of advanced research · 2024Review
- A single nuclei atlas of aging human abdominal subcutaneous white adipose tissue.Research square · 2023Article
- Adipocyte mesenchymal transition contributes to mammary tumor progression.Cell reports · 2022Article
- Aging-dependent regulatory cells emerge in subcutaneous fat to inhibit adipogenesis.Developmental cell · 2021Article
- Identification and characterization of adipose surface epitopes.The Biochemical journal · 2020Review
- Article
- Plasticity of Adipose Tissue-Derived Stem Cells and Regulation of Angiogenesis.Frontiers in physiology · 2018Review
Corrections and comments
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Authors and funding
17 authors at 7 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesCharacterisation of the adipocyte cellular lineage is required for a better understanding of white adipose tissue homoeostasis and expansion. Although several studies have focused on the phenotype of the most immature adipocyte progenitors, very few tools exist to identify committed cells. In haematopoiesis, the CD38 ectoenzyme is largely used to delineate various stages of stem cell lineage commitment. We hypothesise that this marker could be used to identify committed preadipocytes.
methodsComplementary strategies including flow cytometry, cell-sorting approaches, immunohistochemistry and primary cultures of murine adipose progenitors isolated from different fat pads of control or high-fat diet exposed C57BL/6 J mice were used to determine the molecular expression profile, proliferative and differentiation potentials of adipose progenitors expressing the CD38 molecule.
resultsWe demonstrate here that a subpopulation of CD45
conclusionsTogether, these data demonstrate that CD38 represents a new marker that identifies committed preadipocytes as CD45
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Registered trials
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