ArticleScientific reports2017
Improved efficacy of an arthropod toxin expressing fungus against insecticide-resistant malaria-vector mosquitoes.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 50 citations in OpenAlex.
- Engineered Metarhizium fungi produce longifolene to attract and kill mosquitoes.Nature microbiology · 2025Article
- Properties and Pharmacology of Scorpion Toxins and Their Biotechnological Potential in Agriculture and Medicine.Toxins · 2025Review
- Transmission of transgenic mosquito-killing fungi during copulation.Scientific reports · 2025Article
- CRISPR-Cas9-mediated enhancement of Beauveria bassiana virulence with overproduction of oosporein.Fungal biology and biotechnology · 2024Article
- Wolbachia confers protection against the entomopathogenic fungus Metarhizium pingshaense in African Aedes aegypti.Environmental microbiology reports · 2024Article
- Efficacy ofInsects · 2024Article
- Recent Advancements in Pathogenic Mechanisms, Applications and Strategies for Entomopathogenic Fungi in Mosquito Biocontrol.Journal of fungi (Basel, Switzerland) · 2023Review
- Two Novel Mosquitocidal Peptides Isolated from the Venom of the Bahia Scarlet Tarantula (Toxins · 2023Article
- A sugarcane mosaic virus vector for rapid in planta screening of proteins that inhibit the growth of insect herbivores.Plant biotechnology journal · 2021Article
- An efficient Agrobacterium tumefaciens-mediated transformation method for Simplicillium subtropicum (Hypocreales: Cordycipitaceae).Genetics and molecular biology · 2021Article
- Strategies for Heterologous Expression, Synthesis, and Purification of Animal Venom Toxins.Frontiers in bioengineering and biotechnology · 2021Review
- Animal toxins - Nature's evolutionary-refined toolkit for basic research and drug discovery.Biochemical pharmacology · 2020Review
- Infection of highly insecticide-resistant malaria vector Anopheles coluzzii with entomopathogenic bacteria Chromobacterium violaceum reduces its survival, blood feeding propensity and fecundity.Malaria journal · 2020Article
- Opinions of key stakeholders on alternative interventions for malaria control and elimination in Tanzania.Malaria journal · 2020Article
- Application of the Scorpion Neurotoxin AaIT against Insect Pests.International journal of molecular sciences · 2019Review
- High cell density fed-batch production of insecticidal recombinant ribotoxin hirsutellin A from Pichia pastoris.Microbial cell factories · 2018Article
- Native entomopathogenic Metarhizium spp. from Burkina Faso and their virulence against the malaria vector Anopheles coluzzii and non-target insects.Parasites & vectors · 2018Article
- Transgenic Metarhizium pingshaense synergistically ameliorates pyrethroid-resistance in wild-caught, malaria-vector mosquitoes.PloS one · 2018Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 4 countries.
Funding
Abstract
The continued success of malaria control efforts requires the development, study and implementation of new technologies that circumvent insecticide resistance. We previously demonstrated that fungal pathogens can provide an effective delivery system for mosquitocidal or malariacidal biomolecules. Here we compared genes from arthropod predators encoding insect specific sodium, potassium and calcium channel blockers for their ability to improve the efficacy of Metarhizium against wild-caught, insecticide-resistant anophelines. Toxins expressed under control of a hemolymph-specific promoter increased fungal lethality to mosquitoes at spore dosages as low as one conidium per mosquito. One of the most potent, the EPA approved Hybrid (Ca
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.