ArticleCirculation. Arrhythmia and electrophysiology2017
Adult Ventricular Myocytes Segregate KCNQ1 and KCNE1 to Keep the
Article in Circulation. Arrhythmia and electrophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 22 citations in OpenAlex.
- Strategies for prolonging ventricular action potential duration without increasing transmural dispersion of repolarization.Physiological reports · 2025Article
- Long QT Interval Syndrome and Female Sex-Review and Case Report.Reports (MDPI) · 2025Article
- The fully activated open state of KCNQ1 controls the cardiac "fight-or-flight" response.PNAS nexus · 2024Article
- Targeting the ICirculation research · 2024Article
- Persistent PKA activation redistributes NaV1.5 to the cell surface of adult rat ventricular myocytes.The Journal of general physiology · 2024Article
- Is there an emerging role for IJournal of cellular physiology · 2022Article
- Delayed KCNQ1/KCNE1 assembly on the cell surface helps IThe Journal of physiology · 2021Article
- Global identification of S-palmitoylated proteins and detection of palmitoylating (DHHC) enzymes in heart.Journal of molecular and cellular cardiology · 2021Article
- Long QT syndrome - Bench to bedside.Heart rhythm O2 · 2021Article
- The unconventional biogenesis of Kv7.1-KCNE1 complexes.Science advances · 2020Article
- Structure-function relationship of the slow delayed rectifier channel: impactful questions in 2020 and beyond.American journal of physiology. Heart and circulatory physiology · 2020Article
- Article
- Gating and Regulation of KCNQ1 and KCNQ1 + KCNE1 Channel Complexes.Frontiers in physiology · 2020Review
- Dynamic palmitoylation regulates trafficking of K channel interacting protein 2 (KChIP2) across multiple subcellular compartments in cardiac myocytes.Journal of molecular and cellular cardiology · 2019Article
- Article
- β-adrenergic-mediated dynamic augmentation of sarcolemmal CaThe Journal of physiology · 2019Article
- Chronic in vivo angiotensin II administration differentially modulates the slow delayed rectifier channels in atrial and ventricular myocytes.Heart rhythm · 2019Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
backgroundKCNQ1 and KCNE1 assemble to form the slow delayed rectifier ( METHODS AND
resultsWe express fluorescently tagged KCNQ1 and KCNE1 in adult ventricular myocytes and follow their biogenesis and trafficking paths. We also study the distribution patterns of native KCNQ1 and KCNE1, and their relationship to
conclusionsIn adult ventricular myocytes, KCNE1 maintains a stable presence on the cell surface, whereas KCNQ1 is dynamic in its localization. KCNQ1 is largely in an intracellular reservoir under basal conditions but can traffic to the cell surface and boost the
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.