Evidence map›Paper›PMID 28611151›Full record

ArticlePhysiological reports2017

Fate mapping neurons and glia derived from Dbx1-expressing progenitors in mouse preBötzinger complex.

Andrew Kottick, Caroline A Martin, Christopher A Del Negro

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. The sigh and related behaviors.Handbook of clinical neurology · 2022
    Review
  7. Unraveling the Mechanisms Underlying Irregularities in Inspiratory Rhythm Generation in a Mouse Model of Parkinson's Disease.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  8. Review
  9. Article
  10. Article
  11. A spatially dynamic network underlies the generation of inspiratory behaviors.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  12. Article
  13. Article
  14. Review
  15. Breathing matters.Nature reviews. Neuroscience · 2018
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Andrew KottickDepartment of Applied Science, The College of William and Mary, Williamsburg, Virginia.ORCID http://orcid.org/0000-0002-3731-5140
Caroline A MartinDepartment of Applied Science, The College of William and Mary, Williamsburg, Virginia.ORCID http://orcid.org/0000-0002-8191-4968
Christopher A Del NegroDepartment of Applied Science, The College of William and Mary, Williamsburg, Virginia cadeln@wm.edu.ORCID http://orcid.org/0000-0002-7848-8224
William & Mary · US

Funding

Neurophysiology of breathing behavior in neonatal mice in vitroR01HL104127 · NHLBI · COLLEGE OF WILLIAM AND MARY · PI DEL NEGRO, CHRISTOPHER A. · 2010 to 2018
$2.6M
NHLBI NIH HHS R01 HL104127
6 · The paper itself

Abstract

The brainstem preBötzinger complex (preBötC) generates the inspiratory breathing rhythm, and its core rhythmogenic interneurons are derived from Dbx1-expressing progenitors. To study the neural bases of breathing, tamoxifen-inducible Cre-driver mice and Cre-dependent reporters are used to identify, record, and perturb Dbx1 preBötC neurons. However, the relationship between tamoxifen administration and reporter protein expression in preBötC neurons and glia has not been quantified. To address this problem, we crossed mice that express tamoxifen-inducible Cre recombinase under the control of the

Indexed as

AnimalsBrain StemHomeodomain ProteinsInterneuronsMiceMice, TransgenicNeural Stem CellsNeurogliaDbx1 protein, mouseHomeodomain ProteinsBreathingcentral pattern generatorpre‐Bötzinger complexRespiration

Identifiers

PMID28611151
PMCPMC5471439
OpenAlexW2625902955

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.