Evidence map›Paper›PMID 28611040›Full record

ArticleCancer research2017

β-Catenin Is a Candidate Therapeutic Target for Myeloid Neoplasms with del(5q).

Liping Li, Yue Sheng, Wenshu Li, Chao Hu, Nupur Mittal, Kaoru Tohyama, Amber Seba, You-Yang Zhao, Howard Ozer, Tongyu Zhu and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Cancer research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Bone marrow niches in myelodysplastic syndromes.Journal of cancer metastasis and treatment · 2021
    Article
  11. Targeting Casein Kinase 1 (CK1) in Hematological Cancers.International journal of molecular sciences · 2020
    Review
  12. Wnt Signaling in Leukemia and Its Bone Marrow Microenvironment.International journal of molecular sciences · 2020
    Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Liping LiDepartment of Medicine, Division of Hematology/Oncology, University of Illinois at Chicago, Chicago, Illinois.
Yue ShengDepartment of Medicine, Division of Hematology/Oncology, University of Illinois at Chicago, Chicago, Illinois.
Wenshu LiCollege of Arts and Sciences, Shanghai New York University, Shanghai, China.
Chao HuDepartment of Medicine, Division of Hematology/Oncology, University of Illinois at Chicago, Chicago, Illinois.
Nupur MittalDepartment of Pediatrics, Division of Pediatric Hematology Oncology, University of Illinois at Chicago (Fellow, UIC-Rush-Stroger Fellowship Program, Chicago), Chicago, Illinois.
Kaoru TohyamaDepartment of Laboratory Medicine, Kawasaki Medical School, Kurashiki, Okayama, Japan.
Amber SebaDepartment of Medicine, Division of Hematology/Oncology, University of Illinois at Chicago, Chicago, Illinois.
You-Yang ZhaoDepartment of Pharmacology, University of Illinois at Chicago, Chicago, Illinois.
Howard OzerDepartment of Medicine, Division of Hematology/Oncology, University of Illinois at Chicago, Chicago, Illinois.
Tongyu ZhuFudan University Zhong Shan Hospital, Shanghai, China.
Zhijian QianDepartment of Medicine, Division of Hematology/Oncology, University of Illinois at Chicago, Chicago, Illinois. zjqian@uic.edu.
University of Illinois Chicago · USKawasaki Medical School · JPNew York University Shanghai · CNZhongshan Hospital · CN

Funding

Trpm2 Regulation of Phagocyte Bactericidal Activity and Resolution of Lung InjuryP01HL077806 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MALIK, ASRAR B. · 2005 to 2019
$27.0M
Repair mechanisms of sepsis induced endothelial dysfunction and lung injuryR01HL125350 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MALIK, ASRAR B., ZHAO, YOU-YANG · 2014 to 2018
$3.2M
Novel Signalings and Molecular Targets Of Endothelial Regeneration In Aging LungR01HL123957 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI ZHAO, YOU-YANG · 2014 to 2018
$2.0M
The Role of the APC Tumor Suppressor Gene in Hematopoiesis and LeukemogenesisR01CA140979 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI QIAN, ZHIJIAN · 2010 to 2014
$1.6M
The role of EVI1-induced hypermethylation in leukemogenesis.R01HL131444 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI QIAN, ZHIJIAN · 2016 to 2019
$1.6M
The molecular mechanism of clonal dominance in 5q(del) MDSR01DK107615 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI QIAN, ZHIJIAN · 2016 to 2019
$1.4M
NCI NIH HHS R01 CA140979NHLBI NIH HHS P01 HL077806NHLBI NIH HHS R01 HL125350NHLBI NIH HHS R01 HL131444NIDDK NIH HHS R01 DK107615
6 · The paper itself

Abstract

Deletion of the chromosome 5q [del(5q)] is one of the most common cytogenetic abnormalities observed in patients with

Indexed as

Animalsbeta CateninBlotting, WesternCell Line, TumorChromosome DeletionChromosomes, Human, Pair 5Flow CytometryHeterograftsHumansMiceMice, TransgenicMyelodysplastic Syndromesbeta Catenin

Identifiers

PMID28611040
PMCPMC5559383
OpenAlexW2626358972

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.