Evidence map›Paper›PMID 28609468›Full record

ArticlePloS one2017

Going to sleep in the supine position is a modifiable risk factor for late pregnancy stillbirth; Findings from the New Zealand multicentre stillbirth case-control study.

Lesley M E McCowan, John M D Thompson, Robin S Cronin, Minglan Li, Tomasina Stacey, Peter R Stone, Beverley A Lawton, Alec J Ekeroma, Edwin A Mitchell

Registry-linked trialAbstract readMulticenter Study
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04437407 (UniSA BackOff! Study), which is not on this map. Cited by 37 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04437407 naterminatednot on this mapstarted 2020, after this paper: background citation

UniSA BackOff! Study: A Randomized, Controlled, Five-way, Cross-over Trial to Evaluate the Effect of a Positional Therapy Device on Maternal Sleeping Position in the Third Trimester of Pregnancy

TypeinterventionalSponsorShiphrah Biomedical Inc.Ran2020 to 2021Enrolled6ConditionsStillbirth, Infant, Low Birth Weight, Infant, Very Low Birth Weight, Sleep-Disordered BreathingArmsPB2-1 prototype, PB2-2 prototype, PB2-3 prototype, PB2-4 prototype, PB2-5 prototype
3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  10. Objectively Measured Maternal Supine Sleep and Fetal Growth: A Prospective Cohort Study.BJOG : an international journal of obstetrics and gynaecology · 2026
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  11. How maternal position affects umbilical and middle cerebral artery Doppler indices: insights from a scoping review.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lesley M E McCowanDepartment of Obstetrics and Gynaecology, University of Auckland, Auckland, New Zealand.ORCID http://orcid.org/0000-0001-9915-7873
John M D ThompsonDepartment of Obstetrics and Gynaecology, University of Auckland, Auckland, New Zealand.
Robin S CroninDepartment of Obstetrics and Gynaecology, University of Auckland, Auckland, New Zealand.
Minglan LiDepartment of Obstetrics and Gynaecology, University of Auckland, Auckland, New Zealand.
Tomasina StaceySchool of Healthcare, University of Leeds, Leeds, United Kingdom.
Peter R StoneDepartment of Obstetrics and Gynaecology, University of Auckland, Auckland, New Zealand.
Beverley A LawtonWomen's Health Research Centre, University of Otago, Wellington, New Zealand.
Alec J EkeromaDepartment of Obstetrics and Gynaecology, University of Auckland, Auckland, New Zealand.
Edwin A MitchellDepartment of Paediatrics and Child Health, University of Auckland, Auckland, New Zealand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveOur objective was to test the primary hypothesis that maternal non-left, in particular supine going-to-sleep position, would be a risk factor for late stillbirth (≥28 weeks of gestation).

methodsA multicentre case-control study was conducted in seven New Zealand health regions, between February 2012 and December 2015. Cases (n = 164) were women with singleton pregnancies and late stillbirth, without congenital abnormality. Controls (n = 569) were women with on-going singleton pregnancies, randomly selected and frequency matched for health region and gestation. The primary outcome was adjusted odds of late stillbirth associated with self-reported going-to-sleep position, on the last night. The last night was the night before the late stillbirth was thought to have occurred or the night before interview for controls. Going-to-sleep position on the last night was categorised as: supine, left-side, right-side, propped or restless. Multivariable logistic regression adjusted for known confounders.

resultsSupine going-to-sleep position on the last night was associated with increased late stillbirth risk (adjusted odds ratios (aOR) 3.67, 95% confidence interval (CI) 1.74 to 7.78) with a population attributable risk of 9.4%. Other independent risk factors for late stillbirth (aOR, 95% CI) were: BMI (1.04, 1.01 to 1.08) per unit, maternal age ≥40 (2.88, 1.31 to 6.32), birthweight <10th customised centile (2.76, 1.59 to 4.80), and <6 hours sleep on the last night (1.81, 1.14 to 2.88). The risk associated with supine-going-to-sleep position was greater for term (aOR 10.26, 3.00 to 35.04) than preterm stillbirths (aOR 3.12, 0.97 to 10.05).

conclusionsSupine going-to-sleep position is associated with a 3.7 fold increase in overall late stillbirth risk, independent of other common risk factors. A public health campaign encouraging women not to go-to-sleep supine in the third trimester has potential to reduce late stillbirth by approximately 9%.

Indexed as

Self ReportAdolescentAdultCase-Control StudiesFemaleHumansLogistic ModelsMultivariate AnalysisNew ZealandPregnancyRisk AssessmentRisk FactorsSleepStillbirthSupine PositionYoung Adult

Identifiers

PMID28609468
PMCPMC5469491

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.