Evidence map›Paper›PMID 28609356›Full record

GuidelinePancreas2017

The North American Neuroendocrine Tumor Society Consensus Guidelines for Surveillance and Medical Management of Midgut Neuroendocrine Tumors.

Jonathan R Strosberg, Thorvardur R Halfdanarson, Andrew M Bellizzi, Jennifer A Chan, Joseph S Dillon, Anthony P Heaney, Pamela L Kunz, Thomas M O'Dorisio, Riad Salem, Eva Segelov and 10 more

Registry-linked trialAbstract readConsensus StatementPractice GuidelineReview
In one paragraph

Guideline in Pancreas, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04104529 (Establishment of a Clinico-biological Database in Patients Treated With Metabolic Radiotherapy in the Nuclear Medicine Department), which is not on this map. Cited by 158 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
158citing papers in PubMed, 3 pooled it
20.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04104529 narecruitingnot on this mapstarted 2019, after this paper: background citation

Establishment of a Clinico-biological Database in Patients Treated With Metabolic Radiotherapy in the Nuclear Medicine Department

TypeinterventionalSponsorInstitut du Cancer de Montpellier - Val d'AurelleRan2019 to 2026Enrolled350ConditionsThyroid Cancer, Prostate Cancer, Neuroendocrine TumorsArmsBiological collection, tumor collection
3 · Its place in the literature

Who cites it

158 citing papers in PubMed, 3 syntheses or guidelines pooled it, 360 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Efficacy ofCurrent oncology (Toronto, Ont.) · 2020
    Trial
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  8. Article
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  10. Review
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  12. Review
  13. NETest2.0Cancers · 2026
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

98 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 5 institutions in 3 countries.

Jonathan R StrosbergFrom the *Department of GI Oncology, H. Lee Moffitt Cancer Center, Tampa FL; †Division of Medical Oncology, Mayo Clinic, Rochester, MN; ‡Department of Pathology, University of Iowa, Iowa City, IA; §Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA; ∥Department of Medicine, University of Iowa, Iowa City, IA; ¶Departments of Medicine and Neurosurgery, University of California Los Angeles, Los Angeles; and #Department of Medicine, Division of Oncology, Stanford University School of Medicine, Stanford, CA; **Department of Radiology, Northwestern University, Chicago IL; ††Department of Oncology, Monash University and Monash Health, Melbourne, Victoria, Australia; ‡‡Department of Surgery, University of Iowa Carver College of Medicine, Iowa City, IA; §§Oregon Health & Science University and ∥∥North American Neuroendocrine Tumor Society, Portland, OR; ¶¶Division of Cardiothoracic Surgery, Department of Surgery, University of Iowa Carver College of Medicine, Iowa City, IA; ##Sunnybrook Hospital, Toronto, Canada; ***Department of Radiology, University of Pennsylvania, Philadelphia, PA; †††Memorial Sloan Kettering University and ‡‡‡Division of Cardiology, Mount Sinai Hospital, New York, NY; §§§Department of Gastrointestinal Medical Oncology, MD Anderson Cancer Center, Houston TX; and ∥∥∥Department of Medicine, University of California San Francisco, San Francisco, CA.
Thorvardur R Halfdanarson
Andrew M Bellizzi
Jennifer A Chan
Joseph S Dillon
Anthony P Heaney
Pamela L Kunz
Thomas M O'Dorisio
Riad Salem
Eva Segelov
James R Howe
Rodney F Pommier
Kari Brendtro
Mohammad A Bashir
Simron Singh
Michael C Soulen
Laura Tang
Jerome S Zacks
James C Yao
Emily K Bergsland
University of Iowa · USMount Sinai Hospital · USNorthwestern University · USThe University of Texas MD Anderson Cancer Center · USSunnybrook Hospital · CA

Funding

Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Christopher K Laubenthal · 2000 to 2026
$70.0M
Project 4: New Approaches to Improving the Effectiveness of Radionuclide Targeted Treatments in Neuroendocrine TumorsP50CA174521 · NCI · UNIVERSITY OF IOWA · PI ODORISIO, THOMAS · 2015 to 2021
$13.2M
NCI NIH HHS P50 CA174521
6 · The paper itself

Abstract

There have been significant developments in diagnostic and therapeutic options for patients with neuroendocrine tumors (NETs). Key phase 3 studies include the CLARINET trial, which evaluated lanreotide in patients with nonfunctioning enteropancreatic NETs; the RADIANT-2 and RADIANT-4 studies, which evaluated everolimus in functioning and nonfunctioning NETs of the gastrointestinal tract and lungs; the TELESTAR study, which evaluated telotristat ethyl in patients with refractory carcinoid syndrome; and the NETTER-1 trial, which evaluated Lu-DOTATATE in NETs of the small intestine and proximal colon (midgut). Based on these and other advances, the North American Neuroendocrine Tumor Society convened a multidisciplinary panel of experts with the goal of updating consensus-based guidelines for evaluation and treatment of midgut NETs. The medical aspects of these guidelines (focusing on systemic treatment, nonsurgical liver-directed therapy, and postoperative surveillance) are summarized in this article. Surgical guidelines are described in a companion article.

Indexed as

Clinical Decision-MakingConsensusEvidence-Based MedicineHumansIntestinal NeoplasmsMedical OncologyNeuroendocrine TumorsPatient SelectionPredictive Value of TestsRisk FactorsSocieties, MedicalTreatment Outcome

Identifiers

PMID28609356
PMCPMC5642985
OpenAlexW2625330427

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.