Evidence map›Paper›PMID 28609251›Full record

ReviewGut microbes2017

Intestinal microbiota, fecal microbiota transplantation, and inflammatory bowel disease.

Alexa R Weingarden, Byron P Vaughn

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Gut microbes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 277 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
277citing papers in PubMed, 9 pooled it
10.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

277 citing papers in PubMed, 9 syntheses or guidelines pooled it, 452 citations in OpenAlex.

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217 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Alexa R Weingardena Division of Gastroenterology, Hepatology and Nutrition , University of Minnesota , Minneapolis , MN , USA.
Byron P Vaughna Division of Gastroenterology, Hepatology and Nutrition , University of Minnesota , Minneapolis , MN , USA.ORCID 0000-0001-5081-3761
University of Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) is a complex set of diseases that lead to chronic inflammation in the gastrointestinal tract. Although the etiology of IBD is not fully understood, it is well-known that the intestinal microbiota is associated with the development and maintenance of IBD. Manipulation of the gut microbiota, therefore, may represent a target for IBD therapy. Fecal microbiota transplantation (FMT), where fecal microbiota from a healthy donor is transplanted into a patient's GI tract, is already a successful therapy for Clostridium difficile infection. FMT is currently being explored as a potential therapy for IBD as well. In this review, the associations between the gut microbiota and IBD and the emerging data on FMT for IBD will be discussed.

Indexed as

Fecal Microbiota TransplantationGastrointestinal MicrobiomeAnimalsClostridium InfectionsDisease Models, AnimalFecesHelminthiasisHumansInflammatory Bowel DiseasesIntestinesRandomized Controlled Trials as TopicTreatment OutcomeCrohn's diseasefecal microbiota transplantInflammatory Bowel Diseaseulcerative colitis

Identifiers

PMID28609251
PMCPMC5479396
OpenAlexW2587755289

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.