Evidence map›Paper›PMID 28608547›Full record

ArticleJournal of molecular recognition : JMR2017

Computational modeling of the bat HKU4 coronavirus 3CL

Areej Abuhammad, Rua'a A Al-Aqtash, Brandon J Anson, Andrew D Mesecar, Mutasem O Taha

Open access · bronzeAbstract read
In one paragraph

Article in Journal of molecular recognition : JMR, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. HybridACS pharmacology & translational science · 2021
    Article
  3. Review
  4. Review
  5. Article
  6. Current status of antivirals and druggable targets of SARS CoV-2 and other human pathogenic coronaviruses.Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2020
    Review
  7. Article
  8. Article
  9. Computational modeling of the bat HKU4 coronavirus 3CLJournal of molecular recognition : JMR · 2017
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Areej AbuhammadDepartment of Pharmaceutical Sciences, School of Pharmacy, The University of Jordan, Amman, Jordan.ORCID 0000-0003-4978-5059
Rua'a A Al-AqtashDepartment of Pharmaceutical Sciences, School of Pharmacy, The University of Jordan, Amman, Jordan.
Brandon J AnsonDepartment of Biological Sciences, Purdue University, West Lafayette, IN, USA.
Andrew D MesecarDepartment of Biological Sciences, Purdue University, West Lafayette, IN, USA.
Mutasem O TahaDepartment of Pharmaceutical Sciences, School of Pharmacy, The University of Jordan, Amman, Jordan.ORCID 0000-0002-4453-072X
University of Jordan · JOPurdue University West Lafayette · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging virus that poses a major challenge to clinical management. The 3C-like protease (3CL HIGHLIGHTS: MERS-CoV is an emerging virus that is closely related to the bat HKU4-CoV. 3CL

Indexed as

Amino Acid SequenceAnimalsAntiviral AgentsBetacoronavirusBinding SitesChiropteraComputer SimulationLigandsMiddle East Respiratory Syndrome CoronavirusModels, MolecularProtease InhibitorsQuantitative Structure-Activity RelationshipReproducibility of ResultsROC CurveViral ProteinsAntiviral AgentsLigandsProtease InhibitorsViral Proteins3CLpro inhibitorscoronavirusdbCICAMERSpharmacophore modeling

Identifiers

PMID28608547
PMCPMC7166879
OpenAlexW2624828918

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.