Evidence map›Paper›PMID 28608405›Full record

ArticleEuropean journal of immunology2017

Revisiting the specificity of the MHC class II transactivator CIITA in classical murine dendritic cells in vivo.

David A Anderson, Gary E Grajales-Reyes, Ansuman T Satpathy, Carlos E Vasquez Hueichucura, Theresa L Murphy, Kenneth M Murphy

Open access · bronzeAbstract read
In one paragraph

Article in European journal of immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
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  4. Journal of immunology (Baltimore, Md. : 1950) · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

David A AndersonDepartment of Pathology and Immunology, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
Gary E Grajales-ReyesDepartment of Pathology and Immunology, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
Ansuman T SatpathyDepartment of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Carlos E Vasquez HueichucuraHoward Hughes Medical Institute, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
Theresa L MurphyDepartment of Pathology and Immunology, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
Kenneth M MurphyDepartment of Pathology and Immunology, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
Washington University in St. Louis · USStanford University · US

Funding

ANALYSIS OF BIDIRECTIONAL SIGNALING MECHANISMS FOR BTLA AND HVEM IN AUTOIMMUNITYR01AI076427 · NIAID · WASHINGTON UNIVERSITY · PI MURPHY, KENNETH M · 2009 to 2010
$691k
Howard Hughes Medical InstituteNIAID NIH HHS R01 AI076427
6 · The paper itself

Abstract

Ciita was discovered for its role in regulating transcription of major histocompatibility complex class II (MHCII) genes. Subsequently, CIITA was predicted to control many other genes based on reporter and ChIP-seq analysis but few such predictions have been verified in vivo using Ciita

Indexed as

AnimalsDendritic CellsGene Expression RegulationGenes, MHC Class IIHistocompatibility Antigens Class IIInterferon-gammaMiceNuclear ProteinsTrans-ActivatorsTranscription FactorsTranscriptomeHistocompatibility Antigens Class IIInterferon-gammaMHC class II transactivator proteinNuclear ProteinsTrans-ActivatorsTranscription FactorsZbtb46 protein, mouseCiitaDendritic cellTranscription factorZbtb46

Identifiers

PMID28608405
PMCPMC5757839
OpenAlexW2626872696

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.