ArticleJournal of experimental orthopaedics2017
Geometric morphometric analysis reveals age-related differences in the distal femur of Europeans.
Article in Journal of experimental orthopaedics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Clinical anatomy of distal femur and its implications in total knee arthroplasty: a radiological study.Journal of orthopaedic surgery and research · 2026Article
- A robust method for automatic identification of femoral landmarks, axes, planes and bone coordinate systems using surface models.Scientific reports · 2020Article
- Intraoperative morphometric study of distal femur in Brazilian patients undergoing total knee arthroplasty.PloS one · 2020Observational
- State of the art in post-mortem computed tomography: a review of current literature.Virchows Archiv : an international journal of pathology · 2019Review
- Non-Destructive Trace Detection of Explosives Using Pushbroom Scanning Hyperspectral Imaging System.Sensors (Basel, Switzerland) · 2018Article
- Morphometric evaluation of the knee in Chinese population reveals sexual dimorphism and age-related differences.International orthopaedics · 2018Article
- Reliable landmarks for precise topographical analyses of pathological structural changes of the ovine tibial plateau in 2-D and 3-D subspaces.Scientific reports · 2018Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFew studies have looked into age-related variations in femur shape. We hypothesized that three-dimensional (3D) geometric morphometric analysis of the distal femur would reveal age-related differences. The purpose of this study was to show that differences in distal femur shape related to age could be identified, visualized, and quantified using three-dimensional (3D) geometric morphometric analysis.
methodsGeometric morphometric analysis was carried out on CT scans of the distal femur of 256 subjects living in the south of France. Ten landmarks were defined on 3D reconstructions of the distal femur. Both traditional metric and geometric morphometric analyses were carried out on these bone reconstructions. These analyses were used to identify trends in bone shape in various age-based subgroups (<40, 40-60, >60).
resultsOnly the average bone shape of the < 40-year subgroup was statistically different from that of the other two groups. When the population was divided into two subgroups using 40 years of age as a threshold, the subject's age was correctly assigned 80% of the time. DISCUSSION: Age-related differences are present in this bone segment. This reliable, accurate method could be used for virtual autopsy and to perform diachronic and interethnic comparisons. Moreover, this study provides updated morphometric data for a modern population in the south of France.
conclusionManufacturers of knee replacement implants will have to adapt their prosthesis models as the population evolves over time.
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