Evidence map›Paper›PMID 28608248›Full record

ArticleMetabolic brain disease2017

The analgesic effect of trans-resveratrol is regulated by calcium channels in the hippocampus of mice.

Weijie Wang, Yingcong Yu, Jing Li, Lin Wang, Zhi Li, Chong Zhang, Linlin Zhen, Lianshu Ding, Gang Wang, Xiaoyang Sun and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Metabolic brain disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Weijie WangDepartment of Neurosurgery, Huai'an First People's Hospital, Nanjing Medical University, Huai'an, Jiangsu Province, 223300, China.
Yingcong YuDepartment of Gastroenterology, Wenzhou People's Hospital, Wenzhou No. 3 Clinical Institute affiliated to Wenzhou Medical University, Wenzhou, Zhejiang Province, 325000, China.
Jing LiDepartment of Pharmacy, The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province, 266003, China.
Lin WangDepartment of Clinical Pharmacy, Hangzhou First People's Hospital, Nanjing Medical University, Hangzhou, Zhejiang Province, 310006, China.
Zhi LiDepartment of Pharmaceutical Sciences, School of Pharmacy & Pharmaceutical Sciences, The State University of New York at Buffalo, Buffalo, NY, 14214, USA.
Chong ZhangDepartment of Thyroid Gland and Breast Surgery, Huai'an First People's Hospital, Nanjing Medical University, Huai'an, Jiangsu Province, 223300, China.
Linlin ZhenDepartment of Pharmaceutical Sciences, School of Pharmacy & Pharmaceutical Sciences, The State University of New York at Buffalo, Buffalo, NY, 14214, USA.
Lianshu DingDepartment of Neurosurgery, Huai'an First People's Hospital, Nanjing Medical University, Huai'an, Jiangsu Province, 223300, China.
Gang WangDepartment of Clinical Pharmacy, Hangzhou First People's Hospital, Nanjing Medical University, Hangzhou, Zhejiang Province, 310006, China.
Xiaoyang SunDepartment of Neurosurgery, Huai'an First People's Hospital, Nanjing Medical University, Huai'an, Jiangsu Province, 223300, China. xiaoyangsunhayy@163.com.
Ying XuDepartment of Pharmaceutical Sciences, School of Pharmacy & Pharmaceutical Sciences, The State University of New York at Buffalo, Buffalo, NY, 14214, USA. yxu9@buffalo.edu.
Nanjing Medical University · CNHangzhou First People's Hospital · CNHuaian First People’s Hospital · CNUniversity at Buffalo, State University of New York · USAffiliated Hospital of Qingdao University · CNWenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resveratrol has been widely studied in terms of it's potential to slow the progression of many diseases. But little is known about the mechanism of action in neuropathic pain. Neuropathic pain is the main type of chronic pain associated with tissue injury. Calcium channels and calcium/caffeine-sensitive pools are associated with analgesic pathway involving neuropathic pain. Our previous study suggested that the antinociceptive effect of resveratrol was involved in Ca

Indexed as

AnalgesicsAnimalsCalcium Channel BlockersCalcium ChannelsCalcium Chelating AgentsEgtazic AcidHippocampusMiceNimodipinePainPain MeasurementPain ThresholdResveratrolRyanodineStilbenesAnalgesicsCalcium Channel BlockersCalcium ChannelsCalcium Chelating AgentsEgtazic AcidNimodipineResveratrolRyanodineStilbenesAntinociceptiveBDNFCalcium/caffeine-sensitive poolsCalcium channelsCaMKIITrans-resveratrol

Identifiers

PMID28608248
OpenAlexW2626476493

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.