Evidence map›Paper›PMID 28608184›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2018

Assessment of left ventricular contraction patterns using gated SPECT MPI to predict cardiac resynchronization therapy response.

Ningchao Tao, Yuanhao Qiu, Haipeng Tang, Zhiyong Qian, Hongping Wu, Rui Zhu, Yao Wang, Xiaofeng Hou, Weihua Zhou, Jiangang Zou

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. A method using deep learning to discover new predictors from left-ventricular mechanical dyssynchrony for CRT response.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  4. Article
  5. Left ventricular mechanical dyssynchrony in patient with CAD: The Saga continues.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  6. Mechanical dyssynchrony & CRT: Is it time for guideline updates?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  7. Perspective and future direction of intraventricular mechanical dyssynchrony assessment.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  8. Article
  9. Low septal to lateral wallEJNMMI research · 2019
    Article
  10. Advances in Cardiac Resynchronization Therapy.The Journal of innovations in cardiac rhythm management · 2019
    Review
  11. Mechanical dyssynchrony with phase analysis of gated SPECT: Nap time is over.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Ningchao TaoDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Guangzhou Road 300, Nanjing, 210029, Jiangsu, China.
Yuanhao QiuDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Guangzhou Road 300, Nanjing, 210029, Jiangsu, China.
Haipeng TangSchool of Computing, University of Southern Mississippi, Long Beach, MS, 39560, USA.
Zhiyong QianDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Guangzhou Road 300, Nanjing, 210029, Jiangsu, China.
Hongping WuDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Guangzhou Road 300, Nanjing, 210029, Jiangsu, China.
Rui ZhuDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Guangzhou Road 300, Nanjing, 210029, Jiangsu, China.
Yao WangDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Guangzhou Road 300, Nanjing, 210029, Jiangsu, China.
Xiaofeng HouDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Guangzhou Road 300, Nanjing, 210029, Jiangsu, China.
Weihua ZhouSchool of Computing, University of Southern Mississippi, Long Beach, MS, 39560, USA. weihua.zhou@usm.edu.
Jiangang ZouDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Guangzhou Road 300, Nanjing, 210029, Jiangsu, China. jgzou@njmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe U-shaped left ventricular (LV) contraction pattern, identified by MRI or echocardiography, is associated with improved CRT response. Gated SPECT MPI can measure both myocardial viability and mechanical dyssynchrony in a single scan. The aim of this study is to examine the relationship of the LV contraction pattern and the response of CRT in patients with left bundle branch block (LBBB).

methodsFifty-eight patients who met CRT guidelines and who had pre-CRT MPI were enrolled. Myocardial segments with tracer uptake < 50% of maximum were considered as scar. The LV contraction pattern was considered as U-shaped or non-U-shaped (U-shaped has a block line in the direction of contraction propagation). CRT response was defined as an increase in left ventricular ejection fraction ≥ 5% after 6-month follow-up.

resultsTwenty-eight patients (48%) had a U-shaped contraction pattern and thirty patients (52%) had a non-U-shaped contraction pattern. The U-shaped group showed a significantly higher response rate than the non-U-shaped group (90% vs. 57%; P = 0.005). By univariate and multivariate logistic regression analysis, the U-shaped pattern was an independent predictor of CRT response.

conclusionNon-invasive gated SPECT MPI can characterize LV mechanical contraction patterns. A U-shaped contraction pattern identified is associated with improved CRT response. This may prove useful for improved patient selection for CRT.

Indexed as

Myocardial ContractionVentricular Function, LeftAgedCardiac-Gated Single-Photon Emission Computer-Assisted TomographyCardiac Resynchronization TherapyFemaleHumansLogistic ModelsMaleMiddle Agedcontraction patternCRTheart failureleft bundle branch blockSPECT MPI

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.