ArticleAnnals of intensive care2017
Can proportional ventilation modes facilitate exercise in critically ill patients? A physiological cross-over study : Pressure support versus proportional ventilation during lower limb exercise in ventilated critically ill patients.
Article in Annals of intensive care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 19 citations in OpenAlex.
- Does the breathing response limit exercise tolerance in patients weaning from mechanical ventilation?ERJ open research · 2026Article
- Rehabilitating the diaphragm: an integrated approach to intensive care unit-acquired dysfunction in critical illness-a narrative review.Acute and critical care · 2026Article
- Metabolic cost of physical rehabilitation in mechanically ventilated patients in critical care: an observational study.BMJ open respiratory research · 2025Observational
- Breathlessness assessment, management and impact in the intensive care unit: a rapid review and narrative synthesis.Annals of intensive care · 2024Review
- Dyspnoea in acutely ill mechanically ventilated adult patients: an ERS/ESICM statement.Intensive care medicine · 2024Article
- Neurally Adjusted Ventilatory Assist in Acute Respiratory Failure-A Narrative Review.Journal of clinical medicine · 2022Review
- Feasibility of critical care ergometry: Exercise data of patients on mechanical ventilation analyzed as nine-panel plots.Physiological reports · 2022Article
- Respiratory Support Adjustments and Monitoring of Mechanically Ventilated Patients Performing Early Mobilization: A Scoping Review.Critical care explorations · 2021Article
- Article
- Proportional modes versus pressure support ventilation: a systematic review and meta-analysis.Annals of intensive care · 2018Article
Corrections and comments
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Authors and funding
9 authors at 8 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEarly exercise of critically ill patients may have beneficial effects on muscle strength, mass and systemic inflammation. During pressure support ventilation (PSV), a mismatch between demand and assist could increase work of breathing and limit exercise. A better exercise tolerance is possible with a proportional mode of ventilation (Proportional Assist Ventilation, PAV+ and Neurally Adjusted Ventilatory Assist, NAVA). We examined whether, in critically ill patients, PSV and proportional ventilation have different effects on respiratory muscles unloading and work efficiency during exercise.
methodsProspective pilot randomized cross-over study performed in a medico-surgical ICU. Patients requiring mechanical ventilation >48 h were enrolled. At initiation, the patients underwent an incremental workload test on a cycloergometer to determine the maximum level capacity. The next day, 2 15-min exercise, at 60% of the maximum capacity, were performed while patients were randomly ventilated with PSV and PAV+ or NAVA. The change in oxygen consumption (ΔVO
resultsTen patients were examined, 6 ventilated with PSV/PAV+ and 4 with PSV/NAVA. Despite the same mean inspiratory pressure at baseline between the modes, baseline VO
conclusionsProportional ventilation during exercise results in higher work efficiency and less increase in VO
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