Evidence map›Paper›PMID 28607815›Full record

ArticleSurgical neurology international2017

Vertebroplasty for vertebral compression fractures: Placebo or effective?

Arvin R Wali, Joel R Martin, Robert Rennert, Daniel K Resnick, William Taylor, Peter Warnke, Clark C Chen

Open access · hybridAbstract readEditorial
PubMed Full text at PMC Publisher
In one paragraph

Article in Surgical neurology international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Arvin R WaliDepartment of Neurosurgery, University of California, San Diego, California, USA.
Joel R MartinDepartment of Neurosurgery, University of California, San Diego, California, USA.
Robert RennertDepartment of Neurosurgery, University of California, San Diego, California, USA.
Daniel K ResnickDepartment of Neurosurgery, University of Wisconsin, Madison, Wisconsin, USA.
William TaylorDepartment of Neurosurgery, University of California, San Diego, California, USA.
Peter WarnkeDivision of Neurosurgery, University of Chicago, Chicago, Illinois, USA.
Clark C ChenDepartment of Neurosurgery, University of California, San Diego, California, USA.
University of California, Los Angeles · USUniversity of California, San Diego · USUniversity of Chicago · USUniversity of Wisconsin–Madison · US

Funding

UC San Diego Clinical and Translational Research InstituteTL1TR001443 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DEPP, COLIN A. · 2015 to 2019
$3.4M
NCATS NIH HHS TL1 TR001443
6 · The paper itself

Abstract

Vertebral compression fractures (VCFs) are a major cause of pain and disability. Here, we reviewed six randomized control trials (RCTs) focusing on the efficacy vs. placebo effect of vertebroplasty (VP) for symptomatic VCF. Four RCTs involved a nonsurgically treated control group. Two RCTs compared the use of VP vs. a sham surgery control group. Notably, RCTs comparing nonsurgically treated patients as a control group vs. those undergoing VP uniformly reported that VP contributed to improved pain relief. In contrast, RCTs comparing sham surgery vs. VP uniformly reported no significant differences between the two groups.

Indexed as

Placebo effectrandomized-controlled trialssham-controlled surgeryvertebral compression fracturesvertebroplasty

Identifiers

PMID28607815
PMCPMC5461565
OpenAlexW2617838730

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.