Evidence map›Paper›PMID 28607807›Full record

ArticleCancer biology & medicine2017

Immunohistochemical evaluation of vitamin D receptor (VDR) expression in cutaneous melanoma tissues and four VDR gene polymorphisms.

Francesco La Marra, Giuseppe Stinco, Cinzia Buligan, Giovanni Chiriacò, Diego Serraino, Carla Di Loreto, Sabina Cauci

Open access · goldAbstract read
In one paragraph

Article in Cancer biology & medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

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  9. Classification of endplate lesions in the lumbar spine and association with risk factors, biochemistry, and genetics.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2021
    Observational
  10. Serum 25-hydroxyvitamin D level and vitamin D receptor (VDR) polymorphisms in patients infected withJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2020
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Francesco La MarraDepartment of Medical Area, School of Medicine, University of Udine, Udine 33100, Italy.
Giuseppe StincoDepartment of Medical Area, School of Medicine, University of Udine, Udine 33100, Italy.
Cinzia BuliganDepartment of Medical Area, School of Medicine, University of Udine, Udine 33100, Italy.
Giovanni ChiriacòDepartment of Medical Area, School of Medicine, University of Udine, Udine 33100, Italy.
Diego SerrainoDepartment of Medical Area, School of Medicine, University of Udine, Udine 33100, Italy.
Carla Di LoretoDepartment of Medical Area, School of Medicine, University of Udine, Udine 33100, Italy.
Sabina CauciDepartment of Medical Area, School of Medicine, University of Udine, Udine 33100, Italy.
University of Udine · ITCentro di Riferimento Oncologico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objective: Vitamin D receptor (VDR) mediates vitamin D activity. We examined whether VDR expression in excised melanoma tissues is associated with VDR gene (

methods: We evaluated VDR protein expression (by monoclonal antibody immunostaining), melanoma characteristics, and carriage of

results: Stage I melanomas, Breslow thickness of <1.00 mm, level II Clark invasion, Aa heterozygous genotype, and AaTT combined genotype were more frequent in melanomas with high

conclusions: We highlighted that

Indexed as

cutaneous melanomaFokI polymorphismmetastatic melanomapredictive biomarkersskin cancerVDR polymorphismVDR protein expressionVitamin D receptor

Identifiers

PMID28607807
PMCPMC5444928
OpenAlexW2615525959

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.