ArticleJournal of obesity2017
FTO Gene Associates and Interacts with Obesity Risk, Physical Activity, Energy Intake, and Time Spent Sitting: Pilot Study in a Nigerian Population.
Article in Journal of obesity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Associations between Single Nucleotide Polymorphisms and Total Energy, Carbohydrate, and Fat Intakes: A Systematic Review.Advances in nutrition (Bethesda, Md.) · 2018Pooled it
- Associations Between FTO rs9939609 Genotype, Physical Activity, and Dietary Behaviors in Young Adults.Nutrients · 2026Article
- How do lifestyle factors modify the association between genetic predisposition and obesity-related phenotypes? A 4-way decomposition analysis using UK Biobank.BMC medicine · 2024Article
- FTO and Anthropometrics: The Role of Modifiable Factors.Journal of functional morphology and kinesiology · 2022Review
- What is the role of cardiorespiratory fitness and sedentary behavior in relationship between the genetic predisposition to obesity and cardiometabolic risk score?BMC cardiovascular disorders · 2022Article
- Breastfeeding moderates the relationship betweenObesity science & practice · 2022Article
- Dietary Mediators of the Genetic Susceptibility to Obesity-Results from the Quebec Family Study.The Journal of nutrition · 2022Article
- Gut microbiota modulates differential lipid metabolism outcomes associated with FTO gene polymorphisms in response to personalized nutrition intervention.Frontiers in nutrition · 2022Article
- Effects of Gene-Environment Interaction on Obesity among Chinese Adults Born in the Early 1960s.Genes · 2021Article
- The association between FTO genotype with macronutrients and calorie intake in overweight adults.Lipids in health and disease · 2020Article
- Anthropometric and Metabolic Responses inJournal of pediatric genetics · 2020Article
- Ancestry specific associations of FTO gene variant and metabolic syndrome: A longitudinal ARIC study.Medicine · 2020Observational
- Genetic Basis of Obesity and Type 2 Diabetes in Africans: Impact on Precision Medicine.Current diabetes reports · 2019Review
- Influence ofDiabetes, metabolic syndrome and obesity : targets and therapy · 2018Article
- Association between polymorphisms inDiabetes, metabolic syndrome and obesity : targets and therapy · 2018Article
- Interaction between Social/Psychosocial Factors and Genetic Variants on Body Mass Index: A Gene-Environment Interaction Analysis in a Longitudinal Setting.International journal of environmental research and public health · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fat mass and obesity-associated (FTO) gene influences obesity but studies have shown that environmental/lifestyle variables like physical activity (PA), time spent sitting (TSS), and energy intake might mediate the effect. However, this is poorly understood in Nigeria due to scarce studies. We demystified association and interaction between FTO rs9939609, obesity, PA, TSS, and energy intake in Nigeria. FTO gene variant was genotyped by restriction fragment length polymorphism and gene sequencing analysis in 103 people with obesity and 98 controls. Anthropometrics and environmental variables were measured using standard procedures. Significant associations were found between FTO rs9939609 with obesity and environmental/lifestyle variables before and after adjusting for age. Carriers of allele A have significantly higher odds of being overweight/obese using BMI [0.191 (0.102-0.361),
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.