Evidence map›Paper›PMID 28607763›Full record

ArticleActa radiologica open2017

In vitro evaluation of a new iterative reconstruction algorithm for dose reduction in coronary artery calcium scoring.

Tobias Gassenmaier, Thomas Allmendinger, Andreas S Kunz, Maike Veyhl-Wichmann, Süleyman Ergün, Thorsten A Bley, Bernhard Petritsch

Abstract read
In one paragraph

Article in Acta radiologica open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tobias GassenmaierDepartment of Diagnostic and Interventional Radiology, University Hospital of Würzburg, Würzburg, Germany.
Thomas AllmendingerSiemens Healthineers, Forchheim, Germany.
Andreas S KunzDepartment of Diagnostic and Interventional Radiology, University Hospital of Würzburg, Würzburg, Germany.
Maike Veyhl-WichmannInstitute of Anatomy and Cell Biology, University of Würzburg, Würzburg, Germany.
Süleyman ErgünInstitute of Anatomy and Cell Biology, University of Würzburg, Würzburg, Germany.
Thorsten A BleyDepartment of Diagnostic and Interventional Radiology, University Hospital of Würzburg, Würzburg, Germany.
Bernhard PetritschDepartment of Diagnostic and Interventional Radiology, University Hospital of Würzburg, Würzburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronary artery calcium (CAC) scoring is a widespread tool for cardiac risk assessment in asymptomatic patients and accompanying possible adverse effects, i.e. radiation exposure, should be as low as reasonably achievable. PURPOSE: To evaluate a new iterative reconstruction (IR) algorithm for dose reduction of in vitro coronary artery calcium scoring at different tube currents. MATERIAL AND

methodsAn anthropomorphic calcium scoring phantom was scanned in different configurations simulating slim, average-sized, and large patients. A standard calcium scoring protocol was performed on a third-generation dual-source CT at 120 kVp tube voltage. Reference tube current was 80 mAs as standard and stepwise reduced to 60, 40, 20, and 10 mAs. Images were reconstructed with weighted filtered back projection (wFBP) and a new version of an established IR kernel at different strength levels. Calcifications were quantified calculating Agatston and volume scores. Subjective image quality was visualized with scans of an ex vivo human heart.

resultsIn general, Agatston and volume scores remained relatively stable between 80 and 40 mAs and increased at lower tube currents, particularly in the medium and large phantom. IR reduced this effect, as both Agatston and volume scores decreased with increasing levels of IR compared to wFBP (

conclusionNew iterative reconstruction kernels may allow for reduction in tube current for established Agatston scoring protocols and consequently for substantial reduction in radiation exposure.

Indexed as

calcium scoreCardiacheartiterative reconstructionradiation safety

Identifiers

PMID28607763
PMCPMC5453409

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.