ArticleMultiple sclerosis journal - experimental, translational and clinical
Effects of expiratory muscle strength training on maximal respiratory pressure and swallow-related quality of life in individuals with multiple sclerosis.
Article in Multiple sclerosis journal - experimental, translational and clinical. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04009408 (Interventional Study of Expiratory Muscle Strength Training as a Treatment in Neuromuscular Disorders), which is not on this map. Cited by 13 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Interventional Study of Expiratory Muscle Strength Training as a Treatment in Neuromuscular Disorders
Who cites it
13 citing papers in PubMed, 4 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Pooled it
- The effect of breathing training on swallowing function in patients with neurogenic dysphagia: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Pooled it
- Effectiveness of respiratory muscle training in adults with multiple sclerosis: a systematic review and meta-analysis.Frontiers in neurology · 2025Pooled it
- Effect of respiratory training on swallowing function in swallowing disorders: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024Pooled it
- Community exercise for individuals with spinal cord injury with inspiratory muscle training: A pilot study.The journal of spinal cord medicine · 2021Trial
- Effects of expiratory muscle strength training on swallowing in survivors of critical illness: A systematic review and narrative synthesis.Journal of the Intensive Care Society · 2026Article
- Animal-Origin Food Waste Across Global Supply Chains: Trends, Upcycling Strategies, and Circular Economy Solutions.Foods (Basel, Switzerland) · 2026Review
- Breaking boundaries: the transformative role of exercise in managing multiple sclerosis.EXCLI journal · 2024Review
- Respiratory issues in patients with multiple sclerosis as a risk factor during SARS-CoV-2 infection: a potential role for exercise.Molecular and cellular biochemistry · 2023Review
- Clinical Practice Guidelines for Oropharyngeal Dysphagia.Annals of rehabilitation medicine · 2023Article
- Using Ultrasound to Document the Effects of Expiratory Muscle Strength Training (EMST) on the Geniohyoid Muscle.Dysphagia · 2022Article
- Diagnosis and treatment of neurogenic dysphagia - S1 guideline of the German Society of Neurology.Neurological research and practice · 2021Article
- Update on Recent Developments in Communication and Swallowing in Multiple Sclerosis.International journal of MS careArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWeakening and dyscoordination of expiratory muscles in multiple sclerosis (MS) can impair respiratory and swallow function.
objectiveThe objective of this paper is to test a novel expiratory muscle strength training (EMST) device on expiratory pressure, swallow function, and swallow-related quality-of-life (SWAL-QOL) in individuals with MS.
methodsParticipants with MS were randomized to a five-week breathing practice of either positive pressure load (EMST) or near-zero pressure (sham). We compared baseline to post-treatment data according to maximum expiratory pressure (MEP), abnormal airway penetration and aspiration (PAS), and SWAL-QOL.
resultsBoth groups improved in MEP (
conclusionResults suggest that strengthening of expiratory muscles can occur with repetition of focused breathing practice in the absence of high resistance. Conversely, results from the PAS and SWAL-QOL domains suggest that the high resistance of the EMST was required in order to improve the functional safety (reduced penetration/aspiration) and coordination of swallowing, specifically pharyngeal function and saliva management.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.