ArticleMultiple sclerosis journal - experimental, translational and clinical
Skeletal muscle mitochondrial capacity in people with multiple sclerosis.
Article in Multiple sclerosis journal - experimental, translational and clinical. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06083194 (Non-invasive Evaluation of Muscle Oxidative Capacity. Study of Its Relationship With Muscular Endurance and Fatigue in Patients With Multiple Sclerosis), which is not on this map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Non-invasive Evaluation of Muscle Oxidative Capacity. Study of Its Relationship With Muscular Endurance and Fatigue in Patients With Multiple Sclerosis
Who cites it
21 citing papers in PubMed, 32 citations in OpenAlex.
- Skeletal muscle mitochondrial impairment in patients with newly diagnosed multiple sclerosis revealed by ¹H/³¹P magnetic resonance spectroscopy.Scientific reports · 2026Observational
- The Role of Near-Infrared Spectroscopy (NIRS) in Neurological and Neurodegenerative Diseases as Support to Clinical Practice: An Overview of the Literature.Diagnostics (Basel, Switzerland) · 2025Review
- The therapeutic potential of exercise for improving mobility in multiple sclerosis.Frontiers in physiology · 2024Review
- Exploring the impact of ketogenic diet on multiple sclerosis: obesity, anxiety, depression, and the glutamate system.Frontiers in nutrition · 2023Review
- Near-infrared spectroscopy estimation of combined skeletal muscle oxidative capacity and OThe Journal of physiology · 2022Article
- Near Infrared Spectroscopy is not a Surrogate of Venous Occlusion Plethysmography to Assess Microvascular Resting Blood Flow and Function.International journal of exercise science · 2022Article
- The pathophysiology of motor fatigue and fatigability in multiple sclerosis.Frontiers in neurology · 2022Review
- Bilateral NIRS measurements of muscle mitochondrial capacity: Feasibility and repeatability.Physiological reports · 2021Article
- Brain and Muscle: How Central Nervous System Disorders Can Modify the Skeletal Muscle.Diagnostics (Basel, Switzerland) · 2020Review
- Mitochondrial capacity using NIRS and incomplete recovery curves: Proximal and Medial Vastus Lateralis muscle.Proceedings of SPIE--the International Society for Optical Engineering · 2020Article
- Near Infrared Spectroscopy Measurements of Mitochondrial Capacity Using Partial Recovery Curves.Frontiers in physiology · 2020Article
- Shared Regulatory Pathways Reveal Novel Genetic Correlations Between Grip Strength and Neuromuscular Disorders.Frontiers in genetics · 2020Article
- Satiating Effect of a Ketogenic Diet and Its Impact on Muscle Improvement and Oxidation State in Multiple Sclerosis Patients.Nutrients · 2019Article
- Neuromuscular and Muscle Metabolic Functions in MELAS Before and After Resistance Training: A Case Study.Frontiers in physiology · 2019Article
- Performance and Capacity Measurement of the Lower Extremities in Multiple Sclerosis -How to Approach?Noro psikiyatri arsivi · 2018Review
- Review
- Effects of Treadmill Training on Muscle Oxidative Capacity and Endurance in People with Multiple Sclerosis with Significant Walking Limitations.International journal of MS careArticle
- Muscle Dysfunction and Walking Impairment in Women with Multiple Sclerosis.International journal of MS careArticle
- Forearm muscle mitochondrial capacity and resting oxygen uptake: Relationship to symptomatic fatigue in persons with multiple sclerosis.Multiple sclerosis journal - experimental, translational and clinicalArticle
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPeople with multiple sclerosis (MS) have functional disability and may have reduced muscle mitochondrial capacity.
objectiveThe objective of this paper is to measure muscle mitochondrial capacity of leg muscles using near-infrared spectroscopy (NIRS) and compare to functional status. MATERIALS AND
methodsPeople with MS (
resultsMitochondrial capacity was lower in the MS group compared to the CON group (rate constants: 1.13 ± 0.29 vs. 1.68 ± 0.37 min
conclusionNIRS measurements of mitochondrial capacity suggest a 40% deficit in people with MS compared to CONs and this may contribute to walking disability.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.