ArticleElectronic physician2017
Assessment of the diagnostic accuracy of double inversion recovery sequence compared with FLAIR and T2W_TSE in detection of cerebral multiple sclerosis lesions.
Article in Electronic physician, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Enhancing the Visibility of Multiple Sclerosis Lesions using Fused Images of Fluid Attenuated Inversion Recovery (FLAIR) and white matter Attenuated Inversion Recovery (WAIR) MRI Sequences.Current medical imaging · 2026Article
- Superiority of 3D-DIR over 3D-FLAIR in the Detection of Cortical Lesions and Correlation with Disability in Multiple Sclerosis: A Multicenter Study.Diagnostics (Basel, Switzerland) · 2025Article
- Links between Neuroanatomy and Neurophysiology with Turning Performance in People with Multiple Sclerosis.Sensors (Basel, Switzerland) · 2023Article
- Reduced brain oxygen metabolism in patients with multiple sclerosis: Evidence from dual-calibrated functional MRI.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023Article
- Evaluation of subacute subarachnoid haemorrhage detection using a magnetic resonance imaging sequence: Double inversion recovery.BioMedicine · 2020Article
- Double-inversion recovery with synthetic magnetic resonance: a pilot study for assessing synovitis of the knee joint compared to contrast-enhanced magnetic resonance imaging.European radiology · 2019Article
- Brain MRI in patients affected by migraine with aura: is there any cortical lesion?Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2018Article
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4 authors.
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Abstract
backgroundMultiple sclerosis (MS) is a demyelinating disease of the central nervous system. MRI has an important role in early diagnosis of MS within diagnostic criteria.
aimTo determine the diagnostic value of the double inversion recovery (DIR) sequence in detection of brain MS lesions.
methodsIn this cross-sectional study, 55 patients were admitted to the MRI department in Vali-E-Asr Hospital in Qaemshahr, Iran, from May 2016 to February 2016. Imaging was performed on a 1.5T Philips MR system using DIR, fluid attenuated inversion recovery (FLAIR), and T2-weighted turbo spin echo (T2W_TSE) sequences with the same parameters, including field of view (FOV), matrix, slice thickness, voxel size, and number of signal averaging (NSA). The DIR sequence has two different time inversions (TI
resultsMore lesions in number and size were depicted on the DIR sequence compared with FLAIR (p=0.000 with a relative ratio of 6) and T2W_TSE (p=0.000 with a relative ratio of 10). DIR demonstrated significantly more intracortical lesions compared with FLAIR (p=0.000 with a relative ratio of 2.53) and T2W_TSE (p=0.000 and relative ratio of 8.87). There was significantly higher contrast ratio between the white matter lesions and the normal appearing white matter (NAWM) in all anatomical regions especially in deep white matter (p=0.001).
conclusionAn increasing total number of MS lesions can be detected by DIR sequence; thus, we recommend adding DIR sequence in routine MR protocols for MS patients.
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