Evidence map›Paper›PMID 28607590›Full record

ArticleJournal of Cancer2017

Association between SNPs in Long Non-coding RNAs and the Risk of Female Breast Cancer in a Chinese Population.

Tao Xu, Xiu-Xiu Hu, Xiang-Xiang Liu, Han-Jin Wang, Kang Lin, Yu-Qin Pan, Hui-Ling Sun, Hong-Xin Peng, Xiao-Xiang Chen, Shu-Kui Wang and 1 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of Cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06357689 (Studying the Association of Genetic Variations in Long Intergenic Noncoding RNA 00511), which is not on this map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06357689 completednot on this mapstarted 2021, after this paper: background citation

Studying the Association of Genetic Variations in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population

TypeobservationalSponsorAin Shams UniversityRan2021 to 2023Enrolled417ConditionsBreast Cancer
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. The association ofBioscience reports · 2018
    Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Decoding LncRNAs.Cancers · 2021
    Review
  9. Article
  10. Article
  11. Correlations between Genetic Polymorphisms in Long Non-Coding RNAInternational journal of molecular sciences · 2019
    Article
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Tao XuGeneral Clinical Research Center, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Xiu-Xiu HuGeneral Clinical Research Center, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Xiang-Xiang LiuGeneral Clinical Research Center, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Han-Jin WangDepartment of General Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Kang LinGeneral Clinical Research Center, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Yu-Qin PanGeneral Clinical Research Center, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Hui-Ling SunGeneral Clinical Research Center, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Hong-Xin PengGeneral Clinical Research Center, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Xiao-Xiang ChenGeneral Clinical Research Center, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Shu-Kui WangGeneral Clinical Research Center, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Bang-Shun HeGeneral Clinical Research Center, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Nanjing Medical University · CNSoutheast University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long non-coding RNAs (LncRNAs) have been reported to be involved in tumorigenesis and tumor progression. Single nucleotide polymorphisms (SNPs) in the lncRNAs also play a vital role in carcinogenesis. The aim of this study was to assess the relationships between the four selected tagSNPs (rs944289, rs3787016, rs1456315, rs7463708) in the lncRNAs and the risk of female breast cancer in a Chinese population. A case-control study was carried out involving in a total of 439 breast cancer patients and 439 age-matched healthy controls. The genotyping was performed with Sequenom MassARRAY and the expression of estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor-2 (HER-2) in tumor tissues was measured by the immunohistochemistry (IHC) assay. We found that rs3787016 TT genotype (adjusted odds ratio (OR) = 1.62, 95% confidence interval (CI) = 1.09-2.41,

Indexed as

Breast cancerLncRNAsSNPs

Identifiers

PMID28607590
PMCPMC5463430
OpenAlexW2611639705

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.