ArticleNature2017
A retinal code for motion along the gravitational and body axes.
Article in Nature, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers.
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Who cites it
90 citing papers in PubMed.
- Temporal prediction captures retinal spiking responses across animal species.Nature communications · 2026Article
- Diversity and Feature Selectivity of Primate Retinal Ganglion Cells.Annual review of vision science · 2026Review
- Spatial biases in visual feature representation of mouse dorsal lateral geniculate nucleus boutons.iScience · 2026Article
- Temporally segregated functions for Gfi1 in the development and maintenance of direction selectivity in the vertebrate retina.Current biology : CB · 2026Article
- Ecological Visual Processing in the Mouse.Annual review of neuroscience · 2026Review
- Filter, Detector, Predictor: The expanding repertoire of retinal computation in vertebrates.Vision research · 2026Review
- Bipolar cell networks underlying steady-state intensity encoding in intrinsically photosensitive retinal ganglion cells.iScience · 2026Article
- Article
- Domain-like patterning of dendritic asymmetry and orientation defined by gap junctions in the mouse retina.iScience · 2025Article
- Differential topographic organization and retinal inheritance of direction and orientation selectivity in the visual thalamus.Nature communications · 2025Article
- Artificial embodied circuits uncover neural architectures of vertebrate visuomotor behaviors.Science robotics · 2025Article
- Slit2/Robo1 signaling constrains image stabilization responses to preserve ethologically favorable directional asymmetry.Current biology : CB · 2025Article
- Limited transmission of mixed convergent signals at the mouse retinogeniculate synapse.Neuron · 2025Article
- Article
- Activity-dependent development of synaptic circuits mediates direction selectivity in an axis-specific manner.Cell reports · 2025Article
- Functionally distinct GABAergic amacrine cell types regulate spatiotemporal encoding in the mouse retina.Nature neuroscience · 2025Article
- Psychophysical evidence for an internal model of gravity in the visual and vestibular estimates of vertical motion duration.Scientific reports · 2025Article
- Eye saccades align optic flow with retinal specializations during object pursuit in freely moving ferrets.Current biology : CB · 2025Article
- Retinal direction of motion is reliably transmitted to visual cortex through highly selective thalamocortical connections.Current biology : CB · 2025Article
- Layer-specific anatomical and physiological features of the retina's neurovascular unit.Current biology : CB · 2025Article
30 more citing papers are in PubMed but not listed here.
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Authors and funding
8 authors.
Funding
Abstract
Self-motion triggers complementary visual and vestibular reflexes supporting image-stabilization and balance. Translation through space produces one global pattern of retinal image motion (optic flow), rotation another. We examined the direction preferences of direction-sensitive ganglion cells (DSGCs) in flattened mouse retinas in vitro. Here we show that for each subtype of DSGC, direction preference varies topographically so as to align with specific translatory optic flow fields, creating a neural ensemble tuned for a specific direction of motion through space. Four cardinal translatory directions are represented, aligned with two axes of high adaptive relevance: the body and gravitational axes. One subtype maximizes its output when the mouse advances, others when it retreats, rises or falls. Two classes of DSGCs, namely, ON-DSGCs and ON-OFF-DSGCs, share the same spatial geometry but weight the four channels differently. Each subtype ensemble is also tuned for rotation. The relative activation of DSGC channels uniquely encodes every translation and rotation. Although retinal and vestibular systems both encode translatory and rotatory self-motion, their coordinate systems differ.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.