Evidence map›Paper›PMID 28607094›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Pharmacology of the Na

Jeremiah D Osteen, Kevin Sampson, Vivek Iyer, David Julius, Frank Bosmans

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Injury-Induced Effectors of Neuropathic Pain.Molecular neurobiology · 2020
    Review
  14. Article
  15. Selective NaProceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  16. Review
  17. Mechanism-specific assay design facilitates the discovery of Nav1.7-selective inhibitors.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  18. The NaFrontiers in pharmacology · 2018
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jeremiah D OsteenDepartment of Physiology, University of California, San Francisco, CA 94158; jerryosteen@gmail.com david.julius@ucsf.edu frankbosmans@jhmi.edu.
Kevin SampsonDepartment of Pharmacology, College of Physicians and Surgeons, Columbia University, New York, NY 10032.
Vivek IyerDepartment of Pharmacology, College of Physicians and Surgeons, Columbia University, New York, NY 10032.
David JuliusDepartment of Physiology, University of California, San Francisco, CA 94158; jerryosteen@gmail.com david.julius@ucsf.edu frankbosmans@jhmi.edu.
Frank BosmansDepartment of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205; jerryosteen@gmail.com david.julius@ucsf.edu frankbosmans@jhmi.edu.
Columbia University · USUniversity of California, San Francisco · USJohns Hopkins University · US

Funding

Exploiting toxins to probe sensory signalingR37NS065071 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JULIUS, DAVID · 2014 to 2017
$2.0M
ASIC Channels and PainR01NS081115 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JULIUS, DAVID · 2012 to 2016
$1.9M
Voltage-gated sodium channel modulation by Beta1 and Beta4 (R01NS091352)R01NS091352 · NINDS · JOHNS HOPKINS UNIVERSITY · PI BOSMANS, FRANK GERT WERNER · 2015 to 2019
$1.3M
Toxins as molecular probes of pain transduction mechanismsF32NS081907 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI OSTEEN, JEREMIAH · 2012 to 2014
$141k
NINDS NIH HHS F32 NS081907NINDS NIH HHS R01 NS081115NINDS NIH HHS R01 NS091352NINDS NIH HHS R37 NS065071
6 · The paper itself

Abstract

The Na

Indexed as

MutationAcetamidesAnimalsHumansIon Channel GatingNAV1.1 Voltage-Gated Sodium ChannelProtein DomainsSpidersSpider VenomsThiazolesXenopus laevisAcetamidesICA-121431NAV1.1 Voltage-Gated Sodium ChannelSCN1A protein, humanSpider VenomsThiazolesfast inactivationHm1a spider toxinICA-121431Nav1.1slow inactivation

Identifiers

PMID28607094
PMCPMC5495237
OpenAlexW2626581266

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.