Evidence map›Paper›PMID 28607025›Full record

ArticleAntimicrobial agents and chemotherapy2017

Pharmacodynamic Evaluation of Fosfomycin against Escherichia coli and Klebsiella spp. from Urinary Tract Infections and the Influence of pH on Fosfomycin Activities.

Nayara Helisandra Fedrigo, Josmar Mazucheli, James Albiero, Danielle Rosani Shinohara, Fernanda Gomes Lodi, Ana Cristina Dos Santos Machado, Sherwin K B Sy, Maria Cristina Bronharo Tognim

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Fosfomycin Uptake inACS infectious diseases · 2024
    Article
  7. Article
  8. Article
  9. Studies on Virulence and Extended-SpectrumBioMed research international · 2022
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Influence of different peritoneal dialysis fluids on the in vitro activity of fosfomycin against Escherichia coli, Staphylococcus aureus, Staphylococcus epidermidis, and Pseudomonas aeruginosa.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2018
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Nayara Helisandra FedrigoDepartamento de Ciências Básicas da Saúde, Universidade Estadual de Maringá, Maringá, PR, Brazil.
Josmar MazucheliPrograma de Pós-Graduação em Bioestatística, Departamento de Estatística, Universidade Estadual de Maringá, Maringá, PR, Brazil.
James AlbieroDepartamento de Ciências Básicas da Saúde, Universidade Estadual de Maringá, Maringá, PR, Brazil.
Danielle Rosani ShinoharaDepartamento de Ciências Básicas da Saúde, Universidade Estadual de Maringá, Maringá, PR, Brazil.
Fernanda Gomes LodiDepartamento de Ciências Básicas da Saúde, Universidade Estadual de Maringá, Maringá, PR, Brazil.
Ana Cristina Dos Santos MachadoDepartamento de Ciências Básicas da Saúde, Universidade Estadual de Maringá, Maringá, PR, Brazil.
Sherwin K B SyPrograma de Pós-Graduação em Bioestatística, Departamento de Estatística, Universidade Estadual de Maringá, Maringá, PR, Brazil.ORCID 0000-0001-6405-9130
Maria Cristina Bronharo TognimDepartamento de Ciências Básicas da Saúde, Universidade Estadual de Maringá, Maringá, PR, Brazil mcbtognim@uem.br.
Universidade Estadual de Maringá · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fosfomycin is widely used for the treatment of uncomplicated urinary tract infection (UTI), and it has recently been recommended that fosfomycin be used to treat infections caused by multidrug-resistant (MDR) Gram-negative bacilli. Whether urine acidification can improve bacterial susceptibility to fosfomycin oral dosing regimens has not been analyzed. The MIC of fosfomycin for 245 Gram-negative bacterial isolates, consisting of 158

Indexed as

Anti-Bacterial AgentsArea Under CurveEscherichia coliEscherichia coli InfectionsFosfomycinHumansHydrogen-Ion ConcentrationKlebsiellaKlebsiella InfectionsMicrobial Sensitivity TestsUrinary Tract InfectionsAnti-Bacterial AgentsFosfomycinacidic pHEnterobacteriaceaefosfomycinMonte Carlo simulationpharmacodynamicsurinary tract infection

Identifiers

PMID28607025
PMCPMC5527594
OpenAlexW2626751101

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.