Evidence map›Paper›PMID 28607021›Full record

ArticleAntimicrobial agents and chemotherapy2017

Selective Killing of Dormant Mycobacterium tuberculosis by Marine Natural Products.

Carolina Rodrigues Felix, Rashmi Gupta, Sandra Geden, Jill Roberts, Priscilla Winder, Shirley A Pomponi, Maria Cristina Diaz, John K Reed, Amy E Wright, Kyle H Rohde

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 52 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Carolina Rodrigues FelixDivision of Immunity and Pathogenesis, Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, USA.
Rashmi GuptaDivision of Immunity and Pathogenesis, Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, USA.
Sandra GedenDivision of Immunity and Pathogenesis, Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, USA.
Jill RobertsHarbor Branch Oceanographic Institute, Florida Atlantic University, Fort Pierce, Florida, USA.
Priscilla WinderHarbor Branch Oceanographic Institute, Florida Atlantic University, Fort Pierce, Florida, USA.
Shirley A PomponiHarbor Branch Oceanographic Institute, Florida Atlantic University, Fort Pierce, Florida, USA.
Maria Cristina DiazHarbor Branch Oceanographic Institute, Florida Atlantic University, Fort Pierce, Florida, USA.
John K ReedHarbor Branch Oceanographic Institute, Florida Atlantic University, Fort Pierce, Florida, USA.
Amy E WrightHarbor Branch Oceanographic Institute, Florida Atlantic University, Fort Pierce, Florida, USA.
Kyle H RohdeDivision of Immunity and Pathogenesis, Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, USA kyle.rohde@ucf.edu.
Florida Atlantic University · USUniversity of Central Florida · USHarbor Branch Oceanographic Institute · US

Funding

Discovery of marine natural products targeting latent M. tuberculosisR33AI105977 · NIAID · UNIVERSITY OF CENTRAL FLORIDA · PI ROHDE, KYLE H · 2015 to 2017
$1.3M
Discovery of marine natural products targeting latent M. tuberculosisR21AI105977 · NIAID · UNIVERSITY OF CENTRAL FLORIDA · PI ROHDE, KYLE H · 2013 to 2014
$409k
NIAID NIH HHS R21 AI105977NIAID NIH HHS R33 AI105977
6 · The paper itself

Abstract

The dormant phenotype acquired by

Indexed as

Antitubercular AgentsBiological ProductsDrug Evaluation, PreclinicalDrug Resistance, BacterialHumansMicrobial Sensitivity TestsMycobacterium tuberculosisSesquiterpenesTuberculosis, PulmonaryXanthonesAntitubercular AgentsBiological ProductspuupehenoneSesquiterpenesXanthonesdormancydrug discoverydrug screeningmarine natural productsMycobacterium tuberculosisnatural antimicrobial productstuberculosis

Identifiers

PMID28607021
PMCPMC5527660
OpenAlexW2626367965

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.