Evidence map›Paper›PMID 28606175›Full record

ArticleReproductive biology and endocrinology : RB&E2017

Differences in utilization of Intracytoplasmic sperm injection (ICSI) within human services (HHS) regions and metropolitan megaregions in the U.S.

Pavel Zagadailov, Albert Hsu, David B Seifer, Judy E Stern

Abstract read
In one paragraph

Article in Reproductive biology and endocrinology : RB&E, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. ALWAYS ICSI? A SWOT analysis.Journal of assisted reproduction and genetics · 2020
    Review
  5. Do state insurance mandates alter ICSI utilization?Reproductive biology and endocrinology : RB&E · 2020
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pavel ZagadailovDepartment of Ob/Gyn, Dartmouth-Hitchcock Medical Center, Lebanon, NH, 03756, USA.
Albert HsuDepartment of Ob/Gyn, Dartmouth-Hitchcock Medical Center and the Geisel School of Medicine at Dartmouth, One Medical Center Dr, Lebanon, NH, 03756, USA.
David B SeiferDepartment of Ob/Gyn, Dartmouth-Hitchcock Medical Center and the Geisel School of Medicine at Dartmouth, One Medical Center Dr, Lebanon, NH, 03756, USA.
Judy E SternDepartment of Ob/Gyn, Dartmouth-Hitchcock Medical Center and the Geisel School of Medicine at Dartmouth, One Medical Center Dr, Lebanon, NH, 03756, USA. Judy.E.Stern@dartmouth.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnecdotal evidence suggests that US practice patterns for ART differ by geographical region. The purpose of this study was to determine whether use of ICSI differs by region and to evaluate whether these rates are correlated with differences in live birth rates.

methodsPublic data for 2012 were obtained from the Centers for Disease Control and Prevention. Clinics with ≥100 fresh, non-donor cycles were grouped by 10 nationally recognized Department of Health & Human Services regions and 11 metropolitan Megaregions and were compared for use of ICSI, frequency of male factor infertility, and live birth rate in women <35 years.

resultsThere were 274 clinics in the Health & Human Services regions and 247 in the Megaregions. ICSI utilization rates in Health & Human Services groups ranged between 52.5-78.2% (P < 0.0001). Live birth rates per cycle in women <35 years differed (34.1-47.6%; P < 0.0001) but did not correlate with rates of ICSI (R

conclusionsICSI utilization and live birth rates per cycle for each clinic group were significantly different across geographical regions of the U.S. However, higher ICSI utilization rate was not associated with higher rates of male factor infertility nor were they strongly correlated with higher live birth rates per cycle. Studies are needed to understand factors that may influence ICSI overutilization in the U.S.

Indexed as

AdultBirth RateFemaleGeographyHumansInfertility, MaleLive BirthMalePregnancyPregnancy OutcomePregnancy RateRetrospective StudiesSperm Injections, IntracytoplasmicUnited StatesUnited States Dept. of Health and Human ServicesHealth and human services regionICSIIVFLive birth rateMegaregionUtilization

Identifiers

PMID28606175
PMCPMC5469007

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.