ArticleJournal of cardiothoracic surgery2017
Consumption coagulopathy in acute aortic dissection: principles of management.
Article in Journal of cardiothoracic surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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37 citing papers in PubMed, 63 citations in OpenAlex.
- A dynamic recovery failure index after acute type A aortic dissection surgery.Annals of medicine · 2026Article
- Thromboelastography-Based Risk-Stratified Transfusion Strategy in Acute Stanford Type A Aortic Dissection: A Predictive Model and Prospective Validation.Journal of clinical medicine · 2026Article
- Value of Thromboelastography as a Predictor of Postoperative Acute Respiratory Distress Syndrome in Patients With Acute Type A Aortic Dissection.Reviews in cardiovascular medicine · 2026Article
- Incidence of Venous Thromboembolism After Surgery for Acute Stanford Type A Aortic Dissection.Cureus · 2026Article
- Aortic Arch and Frozen Elephant Trunk Surgery: Anesthetic Challenges and Strategies for Organ Protection.Journal of clinical medicine · 2026Review
- Delayed Sternal Closure for High-Risk Cardiac Surgery Patients: Life-Saving Strategy for Improved Outcomes.Journal of clinical medicine · 2026Article
- Association of thrombocytopenia and D-dimer elevation with in-hospital mortality in acute aortic dissection.Annals of medicine · 2025Article
- Unusual consequences of intravenous thrombolysis in a patient undergoing delayed aortic surgery for aortic dissection presenting as acute ischemic stroke: a case report.BMC cardiovascular disorders · 2025Article
- Analysis of the effect of Preset Cabrol in total arch replacement for type A aortic dissection.Journal of thoracic disease · 2025Article
- Intraoperative Hemostatic Agents in Thoracic Aortic Surgery-A Scoping Review.Journal of clinical medicine · 2025Review
- Application of autologous platelet rich plasma in Sun's procedure for acute type A aortic dissection under moderate hypothermia.Frontiers in cardiovascular medicine · 2025Article
- Platelet-to-white blood cell ratio as a predictor of postoperative outcomes in acute type A aortic dissection: a single-center retrospective analysis.Frontiers in cardiovascular medicine · 2025Article
- Prevalence and clinical impact of disseminated intravascular coagulation in acute aortic dissection: a nationwide cohort study.Research and practice in thrombosis and haemostasis · 2025Article
- Article
- Acute type a aortic intramural hematoma complicated with preoperative hemopericardium: early and late surgical outcome analyses.Journal of cardiothoracic surgery · 2024Article
- Analysis of the hemostatic effect of preset wrapping technique for type A aortic dissection with abnormal coagulation.Journal of thoracic disease · 2024Article
- Article
- Prognostic implications of thyroid hormones in acute aortic dissection: mediating roles of renal function and coagulation.Frontiers in endocrinology · 2024Article
- Low preoperative serum fibrinogen level is associated with postoperative acute kidney injury in patients with in acute aortic dissection.Journal of cardiothoracic surgery · 2023Article
- Efficacy of prognostic nutrition index in combination with D-dimer in predicting postoperative clinical adverse events after acute type A aortic dissection: a single center retrospective study.Frontiers in cardiovascular medicine · 2023Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe effect of acute aortic dissection itself on coagulopathy or surgery-related coagulopathy has never been specifically studied. The aim of the present study was to perioperatively describe consumption coagulopathy in patients with acute aortic dissection.
methodsSixty-six patients with acute type A aortic dissection were enrolled in this study from January 2015 to September 2016. Thirty-six patients with thoracic aortic aneurysms were used as a control group during the same period. Consumption coagulopathy was evaluated using standard laboratory tests, enzyme-linked immunosorbent assay and thromboelastograghy at five perioperative time-points.
resultsA significant reduction in clotting factors and fibrinogen was observed at the onset of acute aortic dissection. Enzyme-linked immunosorbent assay and thromboelastograghy also revealed a persistent systemic activation of the coagulation system and the consumption of clotting factors. In contrast, although platelet counts were consistently low, we did not find that platelet function was more impaired in the acute aortic dissection group than the control group.
conclusionsAfter surgery, clotting factors and fibrinogen were more impaired than platelet function. Thus, we proposed that hemostatic therapy should focus on the rapid and sufficient supplementation of clotting factors and fibrinogen to improve consumption coagulopathy in patients with acute aortic dissection.
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