Evidence map›Paper›PMID 28606117›Full record

ArticleBMC neuroscience2017

Investigating the impact of electrical stimulation temporal distribution on cortical network responses.

Francesca Scarsi, Jacopo Tessadori, Michela Chiappalone, Valentina Pasquale

Abstract read
In one paragraph

Article in BMC neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Francesca ScarsiDepartment of Neuroscience and Brain Technologies (NBT), Istituto Italiano di Tecnologia (IIT), Via Morego 30, 16163, Genoa, Italy.
Jacopo TessadoriDepartment of Neuroscience and Brain Technologies (NBT), Istituto Italiano di Tecnologia (IIT), Via Morego 30, 16163, Genoa, Italy.
Michela ChiappaloneDepartment of Neuroscience and Brain Technologies (NBT), Istituto Italiano di Tecnologia (IIT), Via Morego 30, 16163, Genoa, Italy. michela.chiappalone@iit.it.ORCID 0000-0003-1427-5147
Valentina PasqualeDepartment of Neuroscience and Brain Technologies (NBT), Istituto Italiano di Tecnologia (IIT), Via Morego 30, 16163, Genoa, Italy.ORCID 0000-0002-4499-9536

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe brain is continuously targeted by a wealth of stimuli with complex spatio-temporal patterns and has presumably evolved in order to cope with those inputs in an optimal way. Previous studies investigating the response capabilities of either single neurons or intact sensory systems to external stimulation demonstrated that stimuli temporal distribution is an important, if often overlooked, parameter.

resultsIn this study we investigated how cortical networks plated over micro-electrode arrays respond to different stimulation sequences in which inter-pulse intervals followed a 1/f

conclusionsOur results point out that the preference for a scale-free distribution of the stimuli is observed also at network level and should be taken into account in designing more efficient protocols for neuromodulation purposes.

Indexed as

AnimalsBrainElectric StimulationNerve NetNeural PathwaysNeuronsRatsRats, Sprague-DawleyCortical networkElectrical stimulationMicro-electrode arrayNoiseResponse reliabilityScale-free

Identifiers

PMID28606117
PMCPMC5469148

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.