Evidence map›Paper›PMID 28605600›Full record

ArticleJournal of dental research2017

Activin and Bmp4 Signaling Converge on Wnt Activation during Odontogenesis.

H-J E Kwon, S Jia, Y Lan, H Liu, R Jiang

Open access · greenAbstract read
In one paragraph

Article in Journal of dental research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Frontiers in physiology · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Tooth number abnormality: from bench to bedside.International journal of oral science · 2023
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

H-J E Kwon1 Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
S Jia1 Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Y Lan1 Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
H Liu1 Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
R Jiang1 Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Cincinnati Children's Hospital Medical Center · USUniversity of Utah · US

Funding

Molecular Patterning of Mammalian DentitionR01DE018401 · NIDCR · UNIVERSITY OF ROCHESTER · PI JIANG, RULANG · 2009 to 2017
$3.4M
NIDCR NIH HHS R01 DE018401
6 · The paper itself

Abstract

Previous studies show that both activin and Bmp4 act as crucial mesenchymal odontogenic signals during early tooth development. Remarkably, mice lacking activin-βA ( Inhba

Indexed as

ActivinsAnimalsBone Morphogenetic Protein 4Gene Expression Regulation, DevelopmentalIn Situ HybridizationIntercellular Signaling Peptides and ProteinsLaser Capture MicrodissectionLithium ChlorideMembrane ProteinsMiceMice, TransgenicMolarOdontogenesisReal-Time Polymerase Chain ReactionRNA, MessengerSecreted Frizzled-Related ProteinsActivinsBone Morphogenetic Protein 4Dkk2 protein, mouseIntercellular Signaling Peptides and ProteinsLithium ChlorideMembrane ProteinsOsr2 protein, mouseRNA, MessengerSecreted Frizzled-Related ProteinsSfrp2 protein, mouseTranscription Factorscell signalinggeneticsgrowth factorshypodontiamorphogenesistooth development

Identifiers

PMID28605600
PMCPMC5582685
OpenAlexW2625594949

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.