Evidence map›Paper›PMID 28605364›Full record

ArticleJournal of visualized experiments : JoVE2017

Quantitative Visualization of Leukocyte Infiltrate in a Murine Model of Fulminant Myocarditis by Light Sheet Microscopy.

Linda Männ, Anika Klingberg, Matthias Gunzer, Mike Hasenberg

Open access · bronzeAbstract readVideo-Audio Media
In one paragraph

Article in Journal of visualized experiments : JoVE, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Linda MännDepartment of Translational Skin Cancer Research, University of Duisburg/Essen.
Anika KlingbergInstitute for Experimental Immunology and Imaging, University of Duisburg/Essen.
Matthias GunzerInstitute for Experimental Immunology and Imaging, University of Duisburg/Essen.
Mike HasenbergImaging Center Essen, Electron Microscopy Unit, University Hospital of Essen; mike.hasenberg@uni-due.de.
University of Duisburg-Essen · DEImaging Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Light-sheet fluorescence microscopy (LSFM), in combination with chemical clearing protocols, has become the gold standard for analyzing fluorescently labelled structures in large biological specimens, and is down to cellular resolution. Meanwhile, the constant refinement of underlying protocols and the enhanced availability of specialized commercial systems enable us to investigate the microstructure of whole mouse organs and even allow for the characterization of cellular behavior in various live-cell imaging approaches. Here, we describe a protocol for the spatial whole-mount visualization and quantification of the CD45

Indexed as

AnimalsDisease Models, AnimalImage Processing, Computer-AssistedLeukocyte Common AntigensLeukocytesMiceMicroscopy, FluorescenceMyocarditisLeukocyte Common Antigens

Identifiers

PMID28605364
PMCPMC5608177
OpenAlexW2619021909

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.