Observational studyClinical cardiology2017
Population-based values and abnormalities of the electrocardiogram in the general Dutch population: The LifeLines Cohort Study.
Observational study in Clinical cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Prevalence of clinical signs, symptoms and comorbidities at diagnosis of acromegaly: a systematic review in accordance with PRISMA guidelines.Pituitary · 2023Pooled it
- Sex-Specific Prevalence and Distribution of Electrocardiographic Variants in Healthy Vietnamese Freshmen.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2026Article
- Native QRS duration and outcomes in heart failure with mildly reduced ejection fraction: results from a large-scaled registry.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Tele-Electrocardiography and Mortality: Clinical Outcomes in Digital Electrocardiography Cohort-Data from Belo Horizonte, Brazil (CODE-BH).Global heart · 2026Article
- Article
- Increased interleukin-6 levels are associated with atrioventricular conduction delay in severe COVID-19 patients.Journal of arrhythmia · 2024Article
- Advanced Atrioventricular Block in Athletes: Prevalence and Role of Anti-Ro/Sjögren Syndrome-Related Antigen A Antibodies.Journal of the American Heart Association · 2024Article
- Relative fat mass and prediction of incident atrial fibrillation, heart failure and coronary artery disease in the general population.International journal of obesity (2005) · 2023Article
- A large population-based study on the prevalence of electrocardiographic abnormalities: A result of Mashhad stroke and heart atherosclerotic disorder cohort study.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2023Article
- Modeling time-delayed concentration-QT effects with ACT-1014-6470, a novel oral complement factor 5a receptor 1 (C5aPharmacology research & perspectives · 2023Article
- Age and gender differences of basic electrocardiographic values and abnormalities in the general adult population; Tehran Cohort Study.BMC cardiovascular disorders · 2023Article
- Electrocardiogram abnormalities and associated factors among psychiatric patients attending follow up at Jimma Medical Center Psychiatry Clinic, Jimma, Ethiopia: an institution-based cross-sectional study.BMC cardiovascular disorders · 2023Article
- Myotonic dystrophy type 1: A comparison between the adult- and late-onset subtype.Muscle & nerve · 2023Article
- A short P-wave duration is associated with incident heart failure in the elderly: a 15 years follow-up cohort study.Journal of geriatric cardiology : JGC · 2022Article
- Combined Effects of Age and Comorbidities on Electrocardiographic Parameters in a Large Non-Selected Population.Journal of clinical medicine · 2022Article
- Deep neural networks reveal novel sex-specific electrocardiographic features relevant for mortality risk.European heart journal. Digital health · 2022Article
- Prevalence of major and minor electrocardiographic abnormalities and their relationship with cardiovascular risk factors in Angolans.International journal of cardiology. Heart & vasculature · 2022Article
- Unravelling Atrioventricular Block Risk in Inflammatory Diseases: Systemic Inflammation Acutely Delays Atrioventricular Conduction via a Cytokine-Mediated Inhibition of Connexin43 Expression.Journal of the American Heart Association · 2021Article
- The Groningen electrocardiographic criteria for left ventricular hypertrophy: a sex-specific analysis.Scientific reports · 2021Article
- Erythrocytosis in the general population: clinical characteristics and association with clonal hematopoiesis.Blood advances · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOur aim is to present average values and prevalence of electrocardiographic (ECG) abnormalities among the general Dutch population in the LifeLines Cohort. HYPOTHESIS: The ECG values previously studied in the Caucasian population of smaller cohorts will be confirmed with ECG data from LifeLines.
methodsECG data of 152 180 individuals age 18 to 93 years were available. Individuals with cardiovascular risk factors were excluded to analyze the healthy population. Average values of the ECG for the healthy population were presented as means with 95% and 99% confidence intervals and as medians with first and 99th percentiles.
resultsMedian heart rate was highest in the youngest and oldest individuals of the healthy population. Median duration of P wave, PQ interval, and QRS duration were longer in males compared with females. In contrast, median QT interval corrected for heart rate was higher in females. In general, the above-mentioned parameters increased with age. The prevalences of ECG abnormalities adjusted for the Dutch population were 0.9% for atrial fibrillation or flutter, 1.4% for premature atrial complexes, 0.5% for myocardial infarction, 2.1% for ventricular premature complexes, 1.0% for left ventricular hypertrophy, 8.1% for P-R interval >200 ms, and 0.8% for bundle branch block.
conclusionsOur study provides an overview of average values and ECG abnormalities and confirms data of previous smaller studies. In addition, we evaluate the age- and sex-dependent normal limits of the P wave and QRS duration and confirm in detail the frontal plane QRS-T angle on the ECG.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.