ArticleNature microbiology2017
Excess of non-conservative amino acid changes in marine bacterioplankton lineages with reduced genomes.
Article in Nature microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
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- Article
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- Genome reduction occurred in early Prochlorococcus with an unusually low effective population size.The ISME journal · 2024Article
- Chitin utilization by marine picocyanobacteria and the evolution of a planktonic lifestyle.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- A social niche breadth score reveals niche range strategies of generalists and specialists.Nature ecology & evolution · 2023Article
- Abiotic selection of microbial genome size in the global ocean.Nature communications · 2023Article
- Challenges in estimating effective population sizes from metagenome-assembled genomes.Frontiers in microbiology · 2023Article
- Evolutionary jumps in bacterial GC content.G3 (Bethesda, Md.) · 2022Article
- Genome size distributions in bacteria and archaea are strongly linked to evolutionary history at broad phylogenetic scales.PLoS genetics · 2022Article
- Divergent paths in the evolutionary history of maternally transmitted clam symbionts.Proceedings. Biological sciences · 2022Article
- Assessing a Role of Genetic Drift for Deep-Time Evolutionary Events.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Mechanisms driving genome reduction of a novel Roseobacter lineage.The ISME journal · 2021Article
- Snowball Earth, population bottleneck andProceedings. Biological sciences · 2021Article
- Genome Evolution of Filamentous CyanobacteriumMicroorganisms · 2021Article
- Molecular Evolution in Small Steps under Prevailing Negative Selection: A Nearly Universal Rule of Codon Substitution.Genome biology and evolution · 2019Article
- Strong Purifying Selection Is Associated with Genome Streamlining in Epipelagic Marinimicrobia.Genome biology and evolution · 2019Article
- Niche-directed evolution modulates genome architecture in freshwater Planctomycetes.The ISME journal · 2019Article
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4 authors.
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Abstract
Surface ocean waters are dominated by planktonic bacterial lineages with highly reduced genomes. The best examples are the cyanobacterial genus Prochlorococcus, the alphaproteobacterial clade SAR11 and the gammaproteobacterial clade SAR86, which together represent over 50% of the cells in surface oceans. Several studies have identified signatures of selection on these lineages in today's ocean and have postulated selection as the primary force throughout their evolutionary history. However, massive loss of genomic DNA in these lineages often occurred in the distant past, and the selective pressures underlying these ancient events have not been assessed. Here, we probe ancient selective pressures by computing %GC-corrected rates of conservative and radical nonsynonymous nucleotide substitutions. Surprisingly, we found an excess of radical changes in several of these lineages in comparison to their relatives with larger genomes. Furthermore, analyses of allelic genome sequences of several populations within these lineages consistently supported that radical replacements are more likely to be deleterious than conservative changes. Our results suggest coincidence of massive genomic DNA losses and increased power of genetic drift, but we also suggest that additional evidence independent of the nucleotide substitution analyses is needed to support a primary role of genetic drift driving ancient genome reduction of marine bacterioplankton lineages.
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