Evidence map›Paper›PMID 28604679›Full record

ArticleNature microbiology2017

A stabilized microbial ecosystem of self-limiting bacteria using synthetic quorum-regulated lysis.

Spencer R Scott, M Omar Din, Philip Bittihn, Liyang Xiong, Lev S Tsimring, Jeff Hasty

Abstract read
In one paragraph

Article in Nature microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Microbial biotechnology meets ecological theory: a unified framework to design industrial microbial consortia.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Review
  7. Review
  8. Optimization Strategies and Synergistic Applications of EngineeredInternational journal of nanomedicine · 2026
    Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Construction of a syntrophicSynthetic biology (Oxford, England) · 2025
    Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Spencer R ScottDepartment of Bioengineering, University of California, La Jolla, San Diego, California 92093, USA.
M Omar DinDepartment of Bioengineering, University of California, La Jolla, San Diego, California 92093, USA.
Philip BittihnBioCircuits Institute, University of California, La Jolla, San Diego, California 92093, USA.
Liyang XiongBioCircuits Institute, University of California, La Jolla, San Diego, California 92093, USA.
Lev S TsimringBioCircuits Institute, University of California, La Jolla, San Diego, California 92093, USA.
Jeff HastyDepartment of Bioengineering, University of California, La Jolla, San Diego, California 92093, USA.

Funding

SYNTHETIC SYSTEMSP50GM085764 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HASTY, JEFF M, IDEKER, TREY · 2010 to 2018
$23.3M
Engineered Gene Circuits for Basic Science and BiotechnologyR01GM069811 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HASTY, JEFF M, TSIMRING, LEV S · 2004 to 2025
$13.6M
NIGMS NIH HHS P50 GM085764NIGMS NIH HHS R01 GM069811
6 · The paper itself

Abstract

Microbial ecologists are increasingly turning to small, synthesized ecosystems

Indexed as

EcosystemMicrobial InteractionsQuorum SensingSynthetic BiologyBacteriaBacteriolysisCoculture TechniquesEscherichia coliHumansLab-On-A-Chip DevicesModels, BiologicalRhodopseudomonasSalmonella typhimuriumTranscription FactorsTranscription Factors

Identifiers

PMID28604679
PMCPMC5603288

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.