ArticlePsychosomatic medicine2017
Childhood Cognitive Ability and Age-Related Changes in Physical Capability From Midlife: Findings From a British Birth Cohort Study.
Article in Psychosomatic medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Adolescent IQ and performance-based measures of physical function in old age: a 54-year longitudinal study.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- Associations between diabetes status and grip strength trajectory sub-groups in adulthood: findings from over 16 years of follow-up in the MRC National Survey of Health and Development.BMC geriatrics · 2023Article
- Milk intake across adulthood and muscle strength decline from mid- to late life: the MRC National Survey of Health and Development.The British journal of nutrition · 2023Article
- Grip strength from midlife as an indicator of later-life brain health and cognition: evidence from a British birth cohort.BMC geriatrics · 2021Article
- Childhood Cognition and Age-Related Change in Standing Balance Performance From Mid to Later Life: Findings From a British Birth Cohort.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Article
- Developmental factors associated with decline in grip strength from midlife to old age: a British birth cohort study.BMJ open · 2019Article
- Systemic Inflammation and Cardio-Renal Organ Damage Biomarkers in Middle Age Are Associated With Physical Capability Up to 9 Years Later.Circulation · 2019Article
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Authors and funding
3 authors.
Funding
Abstract
objectiveThe aim of the study was to test the hypothesis that higher childhood cognitive ability is associated with reduced risk of decline in physical capability in late midlife.
methodsParticipants were 1954 men and women from the Medical Research Council National Survey of Health and Development with complete data on cognitive ability at age of 15 years and measures of grip strength and chair rise speed at ages of 53 and 60 to 64 years. Using multinomial logistic regression, associations of childhood cognitive ability with categories of change in grip strength and chair rise speed (i.e., decline, stable high, stable low, reference) were investigated. Adjustments were made for potential confounders from early life and adult mediators including health behaviors, educational level, and cognitive ability at age of 53 years.
resultsHigher childhood cognitive scores were associated with reduced risks of decline in grip strength and chair rise speed, for example, the sex-adjusted relative-risk ratio of decline (versus reference) in grip strength per 1SD increase in childhood cognitive score was 0.82 (95% confidence interval = 0.73-0.92). Higher childhood cognitive scores were also associated with reduced risk of stable low and increased likelihood of stable high chair rise speed.
conclusionsThese findings suggest that childhood cognitive ability may be related to decline in physical capability in late midlife. A number of life course pathways are implicated, including those linking childhood and adult cognitive ability. Future research aiming to identify new opportunities to prevent or minimize age-related declines in physical capability may benefit from considering the potential role of neurodevelopmental as well as neurodegenerative pathways.
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