ArticleNeurorehabilitation and neural repair2017
Abnormal EEG Responses to TMS During the Cortical Silent Period Are Associated With Hand Function in Chronic Stroke.
Article in Neurorehabilitation and neural repair, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Resting motor threshold in the course of hand motor recovery after stroke: a systematic review.Journal of neuroengineering and rehabilitation · 2021Pooled it
- Clinical utility and prospective of TMS-EEG: Updated review from an international expert group.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2026Review
- Neurophysiological characterization of stroke recovery: A longitudinal TMS and EEG study.CNS neuroscience & therapeutics · 2024Article
- Intracortical and intercortical networks in patients after stroke: a concurrent TMS-EEG study.Journal of neuroengineering and rehabilitation · 2023Article
- The role of neurophysiological tools in the evaluation of ischemic stroke evolution: a narrative review.Frontiers in neurology · 2023Review
- Electroencephalogram (EEG) With or Without Transcranial Magnetic Stimulation (TMS) as Biomarkers for Post-stroke Recovery: A Narrative Review.Frontiers in neurology · 2022Review
- Motor Cortical Network Flexibility is Associated With Biomechanical Walking Impairment in Chronic Stroke.Neurorehabilitation and neural repair · 2021Article
- Mapping causal circuit dynamics in stroke using simultaneous electroencephalography and transcranial magnetic stimulation.BMC neurology · 2021Article
- Evidence for interhemispheric imbalance in stroke patients as revealed by combining transcranial magnetic stimulation and electroencephalography.Human brain mapping · 2021Article
- Local sleep-like cortical reactivity in the awake brain after focal injury.Brain : a journal of neurology · 2020Article
- Walking Training Enhances Corticospinal Excitability in Progressive Multiple Sclerosis-A Pilot Study.Frontiers in neurology · 2020Article
- Role of Interhemispheric Cortical Interactions in Poststroke Motor Function.Neurorehabilitation and neural repair · 2019Article
- The Effects of Combined Low Frequency Repetitive Transcranial Magnetic Stimulation and Motor Imagery on Upper Extremity Motor Recovery Following Stroke.Frontiers in neurology · 2019Article
- The use of transcranial magnetic stimulation to evaluate cortical excitability of lower limb musculature: Challenges and opportunities.Restorative neurology and neuroscience · 2018Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundAbnormal brain excitability influences recovery after stroke at which time a prolonged transcranial magnetic stimulation (TMS)-induced electromyographic silent period is thought to reflect abnormal inhibitory interneuron excitability. Cortical excitability can be probed directly during the silent period using concurrent electroencephalography (EEG) of TMS-evoked responses.
objectiveThe primary study objectives were to characterize TMS-evoked cortical potentials (TEPs) using EEG and to investigate associations with persistent hand and arm motor dysfunction in individuals with chronic stroke.
methodsThirteen participants with chronic stroke-related mild-moderate arm motor impairment and 12 matched controls completed a single TMS-EEG cortical excitability assessment. TEPs recorded from the vertex during cortical silent period (CSP) assessment and while at rest were used to evaluate differences in cortical excitability between stroke and control participants. Associations between TEPs and CSP duration with measures of upper extremity motor behavior were investigated.
resultsSignificantly increased TEP component peak amplitudes and delayed latencies were observed for stroke participants compared with controls during CSP assessment and while at rest. Delayed early TEP component (P30) peak latencies during CSP assessment were associated with less manual dexterity. CSP duration was prolonged in stroke participants, and correlated with P30 peak latency and paretic arm dysfunction.
conclusionsAbnormal cortical excitability directly measured by early TMS-evoked EEG responses during CSP assessment suggests abnormal cortical inhibition is associated with hand dysfunction in chronic stroke. Further investigation of abnormal cortical inhibition in specific brain networks is necessary to characterize the salient neurophysiologic mechanisms contributing to persistent motor dysfunction after stroke.
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