ReviewJournal of thoracic disease2017
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA)-from morphology to molecular testing.
Review in Journal of thoracic disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Artificial intelligence-assisted endobronchial ultrasound for differentiating between benign and malignant thoracic lymph nodes: a meta-analysis.BMC pulmonary medicine · 2025Pooled it
- Diagnostic yield and feasibility of EBUS-guided cautery-assisted transbronchial forceps biopsy for suspected benign mediastinal and hilar lymphadenopathy: a prospective self-controlled pilot study.BMC pulmonary medicine · 2026Article
- Prognostic significance of post-bronchoscopy sputum cytology in lung cancer diagnosed by bronchoscopy: a retrospective cohort study of 625 patients.Journal of thoracic disease · 2026Article
- Approach to mediastinal cytopathology: a diagnostic overview.Mediastinum (Hong Kong, China) · 2026Review
- Performance of Endobronchial Ultrasound-Guided Cryobiopsy in Diagnosing Thoracic Disorders and Its Role in Next-Generation Sequencing for Non-Small-Cell Lung Cancer.Pulmonary medicine · 2025Article
- Analysis of variation of serum CEA, SCC, CYFRA21-1 in patients with lung cancer and their diagnostic value with EBUS-TBNA.Journal of medical biochemistry · 2024Article
- Article
- A Review of Endobronchial-Ultrasound-Guided Transbronchial Intranodal Forceps Biopsy and Cryobiopsy.Diagnostics (Basel, Switzerland) · 2024Review
- Article
- Assessment of endobronchial ultrasound-guided bronchoscopy (EBUS) intranodal forceps biopsy added to EBUS 19-gauge transbronchial needle aspiration: A blinded pathology panel analysis.Thoracic cancer · 2023Article
- First Asia-Pacific experience of trans-bronchial core biopsy with a Franseen needle.Journal of thoracic disease · 2023Article
- Deep Learning Using Endobronchial-Ultrasound-Guided Transbronchial Needle Aspiration Image to Improve the Overall Diagnostic Yield of Sampling Mediastinal Lymphadenopathy.Diagnostics (Basel, Switzerland) · 2022Article
- Neuroendocrine Tumor Diagnosed Through Endoscopic Ultrasound-Guided Fine-Needle Biopsy of a Lung Mass.ACG case reports journal · 2022Article
- The changes on anesthetic practice for non-intubated bronchoscopic interventions during Covid-19 pandemic.Journal of the Formosan Medical Association = Taiwan yi zhi · 2022Article
- Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration (EBUS-TBNA): Technical Updates and Pathological Yield.Diagnostics (Basel, Switzerland) · 2021Review
- EBUS-TBNA Cytological Samples for Comprehensive Molecular Testing in Non-Small Cell Lung Cancer.Cancers · 2021Article
- Article
- Endobronchial ultrasound-guided intranodal forceps biopsy (EBUS-IFB)-technical review.Journal of thoracic disease · 2019Review
- Endobronchial ultrasound-guided fine-needle aspiration for pulmonary carcinomas genotyping: experience with 398 cases including rapidJournal of thoracic disease · 2018Article
- Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In recent years, endobronchial ultrasound-guided TBNA (EBUS-TBNA) has emerged as an innovative technique for diagnosis and staging of lung cancer and has been successfully introduced into daily clinical practice with several advantages including minimally invasive approach, safe, cost-effective, real time image guidance, broad sampling capability, and rapid on-site evaluation (ROSE). Both cytological and histological approach could be useful to have material for diagnosis, immunohistochemical and molecular analyses which may be very important for targeted therapy with successful rate ranging from 89% to 98%. The utility of ROSE during EBUS-TBNA has been matter of debate. Indeed, although some evidence concluded that ROSE does not increase the diagnostic efficacy of EBUS-TBNA, other demonstrated that it improves the diagnostic yield of the procedure up to 30%, allows to avoid repetition of additional diagnostic procedures and reduces risk of complications. Furthermore the sample preparation by cytopathologist is optimized with the aid of direct macroscopic inspection, optimal smearing techniques, and triage of the sample permitting to obtain adequate tissue for diagnosis, ancillary techniques and molecular testing, when needed. Some pathological issues on EBUS-TBNA are reviewed and discussed with particular focus on ROSE and molecular testing.
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