ArticlePharmacology research & perspectives2017
Anticholinergic drug exposure is associated with delirium and postdischarge institutionalization in acutely ill hospitalized older patients.
Article in Pharmacology research & perspectives, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- Differences of anticholinergic drug burden between older hospitalized patients with and without delirium: a systematic review and meta-analysis based on prospective cohort studies.BMC geriatrics · 2024Pooled it
- Association between anticholinergic drug burden and mortality in older people: a systematic review.European journal of clinical pharmacology · 2020Pooled it
- The Prognostic Value of Anticholinergic Burden Measures in Relation to Mortality in Older Individuals: A Systematic Review and Meta-Analysis.Frontiers in pharmacology · 2020Pooled it
- Why Not Rock the Boat? Deprescribing Anticholinergic Medications That Are No Longer Needed in Persons With Schizophrenia.Focus (American Psychiatric Publishing) · 2025Review
- Exploring the Barriers and Facilitators of Deprescribing in Older Adults: Qualitative Study of Patients and Geriatrics Experts.Journal of Korean medical science · 2025Article
- Association of silodosin, tamsulosin, and naftopidil with delirium: analysis of the pharmacovigilance database in Japan.International journal of clinical pharmacy · 2023Article
- Evaluation of the association of anticholinergic burden and delirium in older hospitalised patients - A cohort study comparing 19 anticholinergic burden scales.British journal of clinical pharmacology · 2022Article
- High anticholinergic burden at admission associated with in-hospital mortality in older patients: A comparison of 19 different anticholinergic burden scales.Basic & clinical pharmacology & toxicology · 2022Article
- Anticholinergic Drug Use on Admission and the Risk of In-Hospital Falls in Older Hospitalized Patients.Clinical interventions in aging · 2022Article
- Anticholinergic Drug Exposure Increases the Risk of Delirium in Older Patients Undergoing Elective Surgery.Frontiers in medicine · 2022Article
- Anticholinergic Burden of Geriatric Ward Inpatients.Medicina (Kaunas, Lithuania) · 2021Article
- A survey about postoperative delirium in older patients among nurses and anaesthetists: implications for future practice and policy.Journal of research in nursing : JRN · 2021Article
- Anticholinergic Burden Does Not Influence Delirium Subtype or the Delirium-Mortality Association in Hospitalized Older Adults: Results from a Prospective Cohort Study.Drugs & aging · 2021Article
- Pattern of treatment of behavioural and psychological symptoms of dementia and pain: evidence on pharmacoutilization from a large real-world sample and from a centre for cognitive disturbances and dementia.European journal of clinical pharmacology · 2021Observational
- Antipsychotics and Lorazepam During Delirium: Are We Harming Older Patients? A Real-Life Data Study.Drugs & aging · 2021Article
- Anticholinergic Drugs in Geriatric Psychopharmacology.Frontiers in neuroscience · 2019Review
- Efficacy of posterior tibial nerve stimulation (PTNS) on overactive bladder in older adults.European geriatric medicine · 2018Article
- Article
- Anticholinergic drug exposure is associated with delirium and postdischarge institutionalization in acutely ill hospitalized older patients.Pharmacology research & perspectives · 2017Article
- Increased neutrophil-lymphocyte ratio in delirium: a pilot study.Clinical interventions in aging · 2017Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several studies investigated the possible association between anticholinergic drugs and diverse clinical outcomes in older persons, but the results are inconsistent. The aim of this study was to investigate whether anticholinergic drug exposure is associated with delirium on admission, length of hospital stay, postdischarge institutionalization and in-hospital mortality in acutely ill hospitalized older patients. In this observational chart review study, we included acutely ill patients aged 65 and older who were admitted to the geriatric ward of the Erasmus University Medical Center, Rotterdam, The Netherlands, between 2012 and 2015 (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.