Evidence map›Paper›PMID 28603312›Full record

SynthesisBulletin of the World Health Organization2017

Community-based approaches for neonatal survival: meta-analyses of randomized trial data.

Claudia Hanson, Sanni Kujala, Peter Waiswa, Tanya Marchant, Joanna Schellenberg

Abstract readMeta-Analysis
In one paragraph

Synthesis in Bulletin of the World Health Organization, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Claudia HansonDepartment of Public Health Sciences, Karolinska Institutet, Widerströmska huset, Stockholm, 171 77, Sweden.
Sanni KujalaLondon School of Hygiene & Tropical Medicine, London, England.
Peter WaiswaSchool of Public Health, Makerere University, Kampala, Uganda.
Tanya MarchantLondon School of Hygiene & Tropical Medicine, London, England.
Joanna SchellenbergLondon School of Hygiene & Tropical Medicine, London, England.

Funding

Medical Research Council MR/K012126/1
6 · The paper itself

Abstract

objectiveTo analyse the impact of community approaches to improving newborn health and survival in low-resource countries.

methodsWe updated previous meta-analyses of published cluster randomized trials of community-based interventions for neonatal survival. For each study we extracted baseline data on the context: geographical area; available facilities and staffing; immediate breastfeeding and facility births; and neonatal mortality. We also extracted data on the primary outcome (neonatal survival) and intermediate outcomes of the interventions (changes in immediate breastfeeding and facility births). We used forest plots and pooled sub-group analysis to seek patterns in associations between the effect size and the context or type of intervention (home-based counselling or women's groups).

findingsWe included 17 trials, spanning years from 2001 to 2013. A 25% reduction in neonatal mortality (relative risk, RR: 0.75; 95% confidence interval, CI: 0.69-0.80) was found when pooling six studies in settings with 44 or more deaths per 1000 live births. In lower-mortality settings (pooling six studies with 32 or fewer deaths per 1000 live births) there was no evidence of an effect. We observed some evidence that community approaches had a stronger effect in south Asia than in sub-Saharan Africa. Community approaches had a lower impact on neonatal mortality in settings where at least 44% of women delivered in a facility.

conclusionAs neonatal mortality declined, the impact of community approaches on survival appeared to be lower, and the role of these approaches in supporting newborn care in weak health systems may need to be re-examined.

Indexed as

Community NetworksSurvivalDeveloping CountriesHealth ResourcesHumansInfantInfant MortalityInfant, NewbornRandomized Controlled Trials as Topic

Identifiers

PMID28603312
PMCPMC5463806

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.