Evidence map›Paper›PMID 28602960›Full record

ArticleThe Journal of steroid biochemistry and molecular biology2018

The impact of VDR expression and regulation in vivo.

Seong Min Lee, Mark B Meyer, Nancy A Benkusky, Charles A O'Brien, J Wesley Pike

Abstract read
In one paragraph

Article in The Journal of steroid biochemistry and molecular biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Specific interactions between fluorinated vitamin-DJournal of molecular modeling · 2026
    Article
  5. Article
  6. Article
  7. Impact of vitamin D and vitamin D receptor activator in diabetic nephropathy.Frontiers in clinical diabetes and healthcare · 2025
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. A longitudinal histologic evaluation of vitamin D receptor expression in the skeletal muscles of patients with a distal radius fracture.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021
    Article
  14. Article
  15. Article
  16. Vitamin D and connective tissue diseases.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2020
    Review
  17. Review
  18. Review
  19. Aligning the Paradoxical Role of Vitamin D in Gastrointestinal Immunity.Trends in endocrinology and metabolism: TEM · 2019
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Seong Min LeeDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, United States.
Mark B MeyerDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, United States.
Nancy A BenkuskyDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, United States.
Charles A O'BrienUniversity of Arkansas for Medical Sciences, Little Rock, AR 72205, United States.
J Wesley PikeDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, United States. Electronic address: pike@biochem.wisc.edu.
University of Wisconsin–Madison · USUniversity of Arkansas for Medical Sciences · US

Funding

BONE CELL REGULATION OF THE VITAMIN D RECEPTOR GENER01AR045173 · NIAMS · UNIVERSITY OF WISCONSIN-MADISON · PI PIKE, J WESLEY · 1999 to 2015
$3.5M
Dynamic Mechanisms of Vitamin D-Induced Gene ExpressionR01DK072281 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI PIKE, J WESLEY · 2005 to 2012
$2.6M
Integrative genomics to define osteocyte differentiation, regulation and functionR01AR064424 · NIAMS · UNIVERSITY OF WISCONSIN-MADISON · PI PIKE, J WESLEY · 2014 to 2018
$1.7M
Vitamin D Ligands and Regulation of Calcium HomeostasisR01DK073995 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI PIKE, J WESLEY · 2008 to 2012
$1.5M
NIAMS NIH HHS R01 AR045173NIAMS NIH HHS R01 AR064424NIDDK NIH HHS R01 DK072281NIDDK NIH HHS R01 DK073995
6 · The paper itself

Abstract

The vitamin D receptor (VDR) mediates the pleiotropic biological actions of 1,25-dihydroxyvitamin D

Indexed as

25-Hydroxyvitamin D3 1-alpha-HydroxylaseAnimalsBone and BonesCell LineFemaleGene ExpressionHumansIntestinesKidneyMaleMice, TransgenicReceptors, Calcitriol25-Hydroxyvitamin D3 1-alpha-HydroxylaseReceptors, Calcitriol1,25-dihydroxyvitamin D(3)Bacterial artificial chromosomeChIP-seqHereditary vitamin D resistant ricketsHumanized VDR mouse modelVitamin D receptor

Identifiers

PMID28602960
PMCPMC5723236
OpenAlexW2622707094

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.