Evidence map›Paper›PMID 28602515›Full record

SynthesisParkinsonism & related disorders2017

The impact of Tai Chi and Qigong mind-body exercises on motor and non-motor function and quality of life in Parkinson's disease: A systematic review and meta-analysis.

R Song, W Grabowska, M Park, K Osypiuk, G P Vergara-Diaz, P Bonato, J M Hausdorff, M Fox, L R Sudarsky, E Macklin and 1 more

3 registry-linked trialsOpen access · greenAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Parkinsonism & related disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 116 papers, 40 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
116citing papers in PubMed, 40 pooled it
9.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04019301 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Caring for Caregivers With Mind-body Exercise

TypeinterventionalSponsorUniversity of HoustonRan2019 to 2022Enrolled47ConditionsCaregiver Distress, Physical Function, Quality of LifeArmsBaduanjin Qigong, Community-based, Baduanjin Qigong, Internet-based
NCT07068217 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Effect of Metronome-Based Structured Rhythmic Exercise Program on Freezing and Gait Parameters in Parkinson Disease

TypeinterventionalSponsorMedipol UniversityRan2025 to 2026Enrolled26ConditionsPARKINSON DISEASE (Disorder)ArmsExercise
NCT07662837 narecruitingnot on this mapstarted 2026, after this paper: background citation

Effects of Tai Chi Therapy Versus Qi-Gong on Postural Control, Functional Balance , and Motor Function in Stage-I Parkinson's Patients.

TypeinterventionalSponsorLahore University of Biological and Applied SciencesRan2026 to 2026Enrolled50ConditionsPARKINSON DISEASE (Disorder)ArmsTai Chi, Qi Gong
3 · Its place in the literature

Who cites it

116 citing papers in PubMed, 40 syntheses or guidelines pooled it, 226 citations in OpenAlex.

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  14. Stress reduction through taiji: a systematic review and meta-analysis.BMC complementary medicine and therapies · 2024
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56 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

R SongCollege of Nursing, Chungnam National University, South Korea. Electronic address: songry@cnu.ac.kr.
W GrabowskaOsher Center for Integrative Medicine, Harvard Medical School and Brigham and Women's Hospital, USA. Electronic address: wgrabowska@coa.edu.
M ParkDepartment of Nursing, Woosong College, South Korea. Electronic address: mkpark@wsi.ac.kr.
K OsypiukOsher Center for Integrative Medicine, Harvard Medical School and Brigham and Women's Hospital, USA. Electronic address: kosypiuk@partners.org.
G P Vergara-DiazDepartment of Physical Medicine & Rehabilitation, Spaulding Rehabilitation Hospital, Harvard Medical School, USA. Electronic address: gvergaradiaz@partners.org.
P BonatoDepartment of Physical Medicine & Rehabilitation, Spaulding Rehabilitation Hospital, Harvard Medical School, USA. Electronic address: pbonato@partners.org.
J M HausdorffSackler Faculty of Medicine, Tel Aviv University, Center for the Study of Movement, Cognition, and Mobility at Tel Aviv Sourasky Medical Center, Tel Aviv-Yafo, Israel. Electronic address: Jeff.hausdorff@gmail.com.
M FoxDepartment of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, USA. Electronic address: Mfox3@bidmc.harvard.edu.
L R SudarskyDepartment of Neurology, Harvard Medical School, Brigham and Women's Hospital, USA. Electronic address: lsudarsky@partners.org.
E MacklinHarvard Medical School, Massachusetts General Hospital, USA. Electronic address: emacklin@mgh.harvard.org.
P M WayneOsher Center for Integrative Medicine, Harvard Medical School and Brigham and Women's Hospital, USA. Electronic address: pwayne@partners.org.
Harvard University · USBrigham and Women's Hospital · USBeth Israel Deaconess Medical Center · USChungnam National University · KRTel Aviv Sourasky Medical Center · ILWoosong University · KR

Funding

Mentoring and research in mind-body and integrative therapiesK24AT009282 · NCCIH · BRIGHAM AND WOMEN'S HOSPITAL · PI WAYNE, PETER MICHAEL · 2017 to 2021
$834k
NCCIH NIH HHS K24 AT009282
6 · The paper itself

Abstract

purposeTo systematically evaluate and quantify the effects of Tai Chi/Qigong (TCQ) on motor (UPDRS III, balance, falls, Timed-Up-and-Go, and 6-Minute Walk) and non-motor (depression and cognition) function, and quality of life (QOL) in patients with Parkinson's disease (PD).

methodsA systematic search in 7 electronic databases targeted clinical studies evaluating TCQ for individuals with PD published through August 2016. Meta-analysis was used to estimate effect sizes (Hedges's g) and publication bias for randomized controlled trials (RCTs). Methodological bias in RCTs was assessed by two raters.

resultsOur search identified 21 studies, 15 of which were RCTs with a total of 735 subjects. For RCTs, comparison groups included no treatment (n = 7, 47%) and active interventions (n = 8, 53%). Duration of TCQ ranged from 2 to 6 months. Methodological bias was low in 6 studies, moderate in 7, and high in 2. Fixed-effect models showed that TCQ was associated with significant improvement on most motor outcomes (UPDRS III [ES = -0.444, p < 0.001], balance [ES = 0.544, p < 0.001], Timed-Up-and-Go [ES = -0.341, p = 0.005], 6 MW [ES = -0.293, p = 0.06], falls [ES = -0.403, p = 0.004], as well as depression [ES = -0.457, p = 0.008] and QOL [ES = -0.393, p < 0.001], but not cognition [ES = -0.225, p = 0.477]). I

conclusionEvidence to date supports a potential benefit of TCQ for improving motor function, depression and QOL for individuals with PD, and validates the need for additional large-scale trials.

Indexed as

Parkinson DiseaseQigongQuality of LifeTai JiMeta analysisMotor activityParkinson diseaseQuality of lifeTai Chi

Identifiers

PMID28602515
PMCPMC5618798
OpenAlexW2617217522

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.