Evidence map›Paper›PMID 28602495›Full record

ArticleSurgery2017

Effects of socioeconomic status on children with well-differentiated thyroid cancer.

Evan F Garner, Ilan I Maizlin, Matthew B Dellinger, Kenneth W Gow, Melanie Goldfarb, Adam B Goldin, John J Doski, Monica Langer, Jed G Nuchtern, Sanjeev A Vasudevan and 2 more

Open access · greenAbstract read
In one paragraph

Article in Surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.

  1. Pooled it
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  9. Long-Term Outcomes among Adolescent and Young Adult Survivors of Acute Leukemia: A Surveillance, Epidemiology, and End Results Analysis.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022
    Article
  10. Article
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  12. Impact of Race, Ethnicity, and Socioeconomic Status over Time on the Long-term Survival of Adolescent and Young Adult Hodgkin Lymphoma Survivors.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2021
    Article
  13. The association of low socioeconomic status with advanced stage thyroid cancer.Journal of Taibah University Medical Sciences · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 1 country.

Evan F GarnerDepartment of Surgery, University of Alabama at Birmingham, Birmingham, AL.
Ilan I MaizlinDepartment of Surgery, University of Alabama at Birmingham, Birmingham, AL.
Matthew B DellingerDivision of Pediatric General and Thoracic Surgery, Seattle Children's Hospital, Seattle, WA.
Kenneth W GowDivision of Pediatric General and Thoracic Surgery, Seattle Children's Hospital, Seattle, WA.
Melanie GoldfarbDepartment of Surgery, John Wayne Cancer Institute at Providence St. John's Health Center, Santa Monica, CA.
Adam B GoldinDivision of Pediatric General and Thoracic Surgery, Seattle Children's Hospital, Seattle, WA.
John J DoskiDepartment of Surgery, Methodist Children's Hospital of South Texas, University of Texas Health Science Center-San Antonio, San Antonio, TX.
Monica LangerDepartment of Surgery, Maine Children's Cancer Program, Tufts University, Portland, ME.
Jed G NuchternMichael E. DeBakey Department of Surgery, Baylor College of Medicine, Texas Children's Hospital, Houston, TX.
Sanjeev A VasudevanMichael E. DeBakey Department of Surgery, Baylor College of Medicine, Texas Children's Hospital, Houston, TX.
Mehul V RavalDivision of Pediatric Surgery, Department of Surgery, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA.
Elizabeth A BeierleDepartment of Surgery, University of Alabama at Birmingham, Birmingham, AL. Electronic address: elizabeth.beierle@childrensal.org.
Seattle Children's Hospital · USUniversity of Alabama at Birmingham · USBaylor College of Medicine · USEmory University · USSaint John's Health Center · USTexas Children's Hospital · USThe University of Texas Health Science Center at San Antonio · USTufts University · US

Funding

Research Training Program in Surgical OncologyT32CA091078 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KENNEDY, GREGORY DEAN · 2002 to 2017
$4.8M
NCI NIH HHS T32 CA091078
6 · The paper itself

Abstract

backgroundWell-differentiated thyroid cancer is the most common endocrine malignancy in children. Adult literature has demonstrated socioeconomic disparities in patients undergoing thyroidectomy, but the effects of socioeconomic status on the management of pediatric well-differentiated thyroid cancer remains poorly understood.

methodsPatients ≤21 years of age with well-differentiated thyroid cancer remains were reviewed from the National Cancer Data Base. Three socioeconomic surrogate variables were identified: insurance type, median income, and educational quartile. Tumor characteristics, diagnostic intervals, and clinical outcomes were compared within each socioeconomic surrogate variable.

resultsA total of 9,585 children with well-differentiated thyroid cancer remains were reviewed. In multivariate analysis, lower income, lower educational quartile, and insurance status were associated with higher stage at diagnosis. Furthermore, lower income quartile was associated with a longer time from diagnosis to treatment (P < .002). Similarly, uninsured children had a longer time from diagnosis to treatment (28 days) compared with those with government (19 days) or private (18 days) insurance (P < .001). Despite being diagnosed at a higher stage and having a longer time interval between diagnosis and treatment, there was no significant difference in either overall survival or rates of unplanned readmissions based on any of the socioeconomic surrogate variables.

conclusionChildren from lower income families and those lacking insurance experienced a longer period from diagnosis to treatment of their well-differentiated thyroid cancer remains. These patients also presented with higher stage disease. These data suggest a delay in care for children from low-income families. Although these findings did not translate into worse outcomes for well-differentiated thyroid cancer remains, future efforts should focus on reducing these differences.

Indexed as

AdolescentChildCohort StudiesDatabases, FactualDisease-Free SurvivalFemaleHealthcare DisparitiesHumansInsurance CoverageKaplan-Meier EstimateMaleMedically UninsuredNeeds AssessmentPostoperative ComplicationsRetrospective StudiesRisk Assessment

Identifiers

PMID28602495
PMCPMC5554720
OpenAlexW2624655131

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.