Observational studyPsychosomatics
Pre-existing Psychiatric Illness is Associated With Increased Risk of Recurrent Takotsubo Cardiomyopathy.
Observational study in Psychosomatics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- Prognostic factors of Takotsubo cardiomyopathy: a systematic review.ESC heart failure · 2021Pooled it
- Bridging Minds and Hearts by Exploring the Comorbidities Between Anxiety, Depression, and Takotsubo Cardiomyopathy: A Scoping Review.Journal of clinical medicine · 2026Review
- Use of Serotonin and Catecholamine Reuptake Inhibitors and Onset of Takotsubo Syndrome.Biopsychosocial science and medicine · 2026Article
- Age- and sex-based risk stratification in takotsubo syndrome: a Japanese nationwide registry study.Frontiers in cardiovascular medicine · 2026Article
- When a Woman's Heart Fails to Contain: Takotsubo Syndrome as a Gendered Collapse of Emotional Regulation.Life (Basel, Switzerland) · 2025Review
- Emotional Dysregulation and Autonomic Dysfunction in Takotsubo Cardiomyopathy Patients.Cureus · 2025Article
- Peripartum Cardiomyopathy and Takotsubo Cardiomyopathy: Rare Contributors to Cardiac Causes of Maternal Mortality.Cureus · 2024Article
- Lithium Toxicity with Sinus Bradycardia and Takotsubo Syndrome in a Patient with Bipolar Disorder.Anatolian journal of cardiology · 2024Article
- Evaluation of Recurrent Takotsubo Syndrome.JACC. Advances · 2024Article
- Super Recurrence of Takotsubo Syndrome: Clinical Characteristics and Late Cardiac Outcomes.Journal of the American Heart Association · 2023Article
- Pathophysiology of stress cardiomyopathy: A comprehensive literature review.Annals of medicine and surgery (2012) · 2022Review
- The Swiss cheese model in takotsubo syndrome.European heart journal. Case reports · 2022Article
- Identifying different phenotypes in takotsubo cardiomyopathy by latent class analysis.ESC heart failure · 2021Article
- Takotsubo Syndrome: Optimizing Care with a Multidisciplinary Approach.Journal of multidisciplinary healthcare · 2021Review
- Takotsubo Syndrome: Clinical Manifestations, Etiology and Pathogenesis.Current cardiology reviews · 2021Article
- Takotsubo syndrome in bipolar affective disorder with alcohol withdrawal syndrome.BMJ case reports · 2020Article
- Role of Depression and Anxiety Disorders in Takotsubo Syndrome: The Psychiatric Side of Broken Heart.Cureus · 2020Review
- The authors respond.Proceedings (Baylor University. Medical Center) · 2020Article
- Rare Association of Takotsubo Cardiomyopathy with Right Bundle Branch Block in the Dual Setting of Asthma Exacerbation and Psychiatric Illness.The American journal of case reports · 2020Article
- Takotsubo cardiomyopathy and acute manic attack.Proceedings (Baylor University. Medical Center) · 2020Article
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundThe increased prevalence of psychiatric illness among patients with takotsubo cardiomyopathy (TC) has been previously described.
objectivesWe sought to assess the effect of pre-existing psychiatric illness on clinical outcomes following the diagnosis of TC.
methodsAdults diagnosed with TC at Vanderbilt University Medical Center between 1999 and 2015 were included in the study. Medical records were retrospectively reviewed to identify any pre-existing mood, anxiety, or schizophrenia-spectrum illness before TC presentation. Multivariable logistic regression was used to test for independent association of pre-existing psychiatric illness with 30-day mortality and recurrent TC; Cox proportional hazard analysis was used to evaluate for association with long-term mortality.
resultsAmong 306 patients diagnosed with TC during the study period, 114 (37%) had a pre-existing psychiatric illness. In all, 43 (14%) and 88 (29%) patients died within 30 days of index diagnosis and as of last medical record review, respectively. Of the 269 who survived their index hospitalization, 19 (7%) had a confirmed recurrent episode of TC. In multivariable analyses, pre-existing psychiatric illness was not associated with increased 30-day (P = 0.320) or long-term (P = 0.621) mortality. Pre-existing psychiatric illness was associated with higher risk of recurrent TC (odds ratio = 7.44, 95% CI: 2.30-24.01, P < 0.001).
conclusionsPre-existing psychiatric illness was associated with an increased risk of recurrent TC. No significant association was noted between pre-existing psychiatric illness and survival.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.