Evidence map›Paper›PMID 28602082›Full record

ArticleEnvironmental science & technology2017

Linking Genes to Microbial Biogeochemical Cycling: Lessons from Arsenic.

Yong-Guan Zhu, Xi-Mei Xue, Andreas Kappler, Barry P Rosen, Andrew A Meharg

Open access · greenAbstract read
In one paragraph

Article in Environmental science & technology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
18.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 323 citations in OpenAlex.

  1. Article
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  4. Review
  5. Article
  6. Microbial necromass carbon enhances arsenic methylation in paddy soils.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Mechanisms of Arsenic Interaction inInternational journal of molecular sciences · 2025
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Growth substrate limitation enhances anaerobic arsenic methylation byApplied and environmental microbiology · 2024
    Article
  14. Article
  15. Article
  16. Article
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  18. Review
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 4 countries.

Yong-Guan ZhuKey Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences , Xiamen 361021, China.ORCID http://orcid.org/0000-0003-3861-8482
Xi-Mei XueKey Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences , Xiamen 361021, China.
Andreas KapplerGeomicrobiology, Center for Applied Geosciences, University of Tübingen , Tübingen 72076, Germany.ORCID http://orcid.org/0000-0002-3558-9500
Barry P RosenDepartment of Cellular Biology and Pharmacology, Herbert Wertheim College of Medicine, Florida International University , Miami, Florida 33199, United States.ORCID http://orcid.org/0000-0002-5230-4271
Andrew A MehargInstitute for Global Food Security, Queen's University Belfast , Belfast BT9 5HN, United Kingdom.ORCID http://orcid.org/0000-0003-2019-0449
Chinese Academy of Sciences · CNFlorida International University · USQueen's University Belfast · GB

Funding

Mechanisms of arsenical transportR37GM055425 · NIGMS · WAYNE STATE UNIVERSITY · PI ROSEN, BARRY P. · 2005 to 2014
$4.4M
Mechanisms of Arsenic Transport and BiotransformationsR01GM055425 · NIGMS · WAYNE STATE UNIVERSITY · PI ROSEN, BARRY P. · 1997 to 2019
$3.8M
The human arsenic methylation pathwayR01ES023779 · NIEHS · FLORIDA INTERNATIONAL UNIVERSITY · PI ROSEN, BARRY P. · 2015 to 2019
$1.6M
NIEHS NIH HHS R01 ES023779NIGMS NIH HHS R01 GM055425
6 · The paper itself

Abstract

The biotransformation of arsenic is highly relevant to the arsenic biogeochemical cycle. Identification of the molecular details of microbial pathways of arsenic biotransformation coupled with analyses of microbial communities by meta-omics can provide insights into detailed aspects of the complexities of this biocycle. Arsenic transformations couple to other biogeochemical cycles, and to the fate of both nutrients and other toxic environmental contaminants. Microbial redox metabolism of iron, carbon, sulfur, and nitrogen affects the redox and bioavailability of arsenic species. In this critical review we illustrate the biogeochemical processes and genes involved in arsenic biotransformations. We discuss how current and future metagenomic-, metatranscriptomic-, metaproteomic-, and metabolomic-based methods will help to decipher individual microbial arsenic transformation processes, and their connections to other biogeochemical cycle. These insights will allow future use of microbial metabolic capabilities for new biotechnological solutions to environmental problems. To understand the complex nature of inorganic and organic arsenic species and the fate of environmental arsenic will require integrating systematic approaches with biogeochemical modeling. Finally, from the lessons learned from these studies of arsenic biogeochemistry, we will be able to predict how the environment changes arsenic, and, in response, how arsenic biotransformations change the environment.

Indexed as

MetagenomicsArsenicBiotransformationCarbonEnvironmentIronArsenicCarbonIron

Identifiers

PMID28602082
PMCPMC5871744
OpenAlexW2621437326

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.