Evidence map›Paper›PMID 28601227›Full record

ReviewThe Enzymes

TrmD: A Methyl Transferase for tRNA Methylation With m

Ya-Ming Hou, Ryuma Matsubara, Ryuichi Takase, Isao Masuda, Joanna I Sulkowska

Open access · greenAbstract readReview
In one paragraph

Review in The Enzymes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 43 citations in OpenAlex.

  1. Nicotinamide-Based Covalent Inhibitors of tRNA (mACS medicinal chemistry letters · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Knotted artifacts in predicted 3D RNA structures.PLoS computational biology · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Are there double knots in proteins? Prediction andFrontiers in molecular biosciences · 2023
    Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Adaptor Molecules Epitranscriptome Reprograms Bacterial Pathogenicity.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Ya-Ming HouThomas Jefferson University, Philadelphia, PA, United States. Electronic address: ya-ming.hou@jefferson.edu.
Ryuma MatsubaraThomas Jefferson University, Philadelphia, PA, United States.
Ryuichi TakaseThomas Jefferson University, Philadelphia, PA, United States.
Isao MasudaThomas Jefferson University, Philadelphia, PA, United States.
Joanna I SulkowskaCenter of New Technologies, University of Warsaw, Warsaw, Poland.
Thomas Jefferson University · USUniversity of Warsaw · PL

Funding

AdoMet-dependent tRNA methyl transferasesR01GM114343 · NIGMS · THOMAS JEFFERSON UNIVERSITY · PI HOU, YA-MING · 2015 to 2018
$1.3M
Probes for a tRNA modification enzymeU01GM108972 · NIGMS · THOMAS JEFFERSON UNIVERSITY · PI HOU, YA-MING · 2015 to 2016
$603k
Probes for a tRNA modification enzymeR01GM108972 · NIGMS · THOMAS JEFFERSON UNIVERSITY · PI HOU, YA-MING · 2014 to 2014
$295k
NIGMS NIH HHS R01 GM108972NIGMS NIH HHS R01 GM114343NIGMS NIH HHS U01 GM108972
6 · The paper itself

Abstract

TrmD is an S-adenosyl methionine (AdoMet)-dependent methyl transferase that synthesizes the methylated m

Indexed as

MethylationRNA Processing, Post-TranscriptionalEscherichia coliEscherichia coli ProteinsRNA, TransferSubstrate SpecificitytRNA MethyltransferasesEscherichia coli ProteinsRNA, TransferTrmD protein, E colitRNA MethyltransferasesFrameshiftsm(1)G37-tRNAMg(2+) transportProtein trefoil knotS-adenosyl methioninetRNA(Pro)

Identifiers

PMID28601227
PMCPMC6054489
OpenAlexW2621855997

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.