Evidence map›Paper›PMID 28600646›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2017

Increased FDG uptake on late-treatment PET in non-tumour-affected oesophagus is prognostic for pathological complete response and disease recurrence in patients undergoing neoadjuvant radiochemotherapy.

Sebastian Zschaeck, Frank Hofheinz, Klaus Zöphel, Rebecca Bütof, Christina Jentsch, Julia Schmollack, Steffen Löck, Jörg Kotzerke, Gustavo Baretton, Jürgen Weitz and 2 more

Abstract readEvaluation Study
PubMed Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Value of PET imaging for radiation therapy.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2021
    Review
  4. Role of precision imaging in esophageal cancer.Journal of thoracic disease · 2020
    Review
  5. Article
  6. A model combining age, equivalent uniform dose and IL-8 may predict radiation esophagitis in patients with non-small cell lung cancer.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 1 country.

Sebastian ZschaeckDepartment of Radiation Oncology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstr. 74, 01307, Dresden, Germany. sebastian.zschaeck@uniklinikum-dresden.de.
Frank HofheinzPET Center, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany.
Klaus ZöphelGerman Cancer Consortium (DKTK), Dresden, Germany.
Rebecca BütofDepartment of Radiation Oncology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstr. 74, 01307, Dresden, Germany.
Christina JentschDepartment of Radiation Oncology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstr. 74, 01307, Dresden, Germany.
Julia SchmollackDepartment of Radiation Oncology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstr. 74, 01307, Dresden, Germany.
Steffen LöckDepartment of Radiation Oncology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstr. 74, 01307, Dresden, Germany.
Jörg KotzerkeGerman Cancer Consortium (DKTK), Dresden, Germany.
Gustavo BarettonGerman Cancer Consortium (DKTK), Dresden, Germany.
Jürgen WeitzGerman Cancer Consortium (DKTK), Dresden, Germany.
Michael BaumannDepartment of Radiation Oncology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstr. 74, 01307, Dresden, Germany.
Mechthild KrauseDepartment of Radiation Oncology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstr. 74, 01307, Dresden, Germany.
University Hospital Carl Gustav Carus · DEGerman Cancer Society · DETechnische Universität Dresden · DEDeutschen Konsortium für Translationale Krebsforschung · DEGerman Cancer Research Center · DEHeidelberg University · DEHelmholtz-Zentrum Dresden-Rossendorf · DENational Center for Tumor Diseases · DE

Funding

Bundesministerium für Bildung und Forschung 03ZIK42
6 · The paper itself

Abstract

purposeEarly side effects including oesophagitis are potential prognostic factors in patients undergoing radiochemotherapy (RCT) for locally advanced oesophageal cancer (LAEC). We assessed the prognostic value of

methodsThis retrospective evaluation included 64 patients with LAEC who had completed neoadjuvant RCT and had successful oncological resection. All patients underwent FDG PET/CT before and after RCT. In the restaging PET scan maximum and mean standardized uptake values (SUV

resultsIncreased FDG uptake, measured in terms of SUV

conclusionsFDG uptake in irradiated normal tissues measured on restaging PET has significant prognostic value in patients undergoing neoadjuvant RCT for LAEC. This effect may potentially be of use in treatment personalization.

Indexed as

CarcinomaChemoradiotherapy, AdjuvantEsophageal NeoplasmsFemaleFluorodeoxyglucose F18HumansMaleMiddle AgedNeoplasm Recurrence, LocalPositron-Emission TomographyRadiopharmaceuticalsFluorodeoxyglucose F18RadiopharmaceuticalsFDG petInflammationOesophageal cancerRadiochemotherapySide effects

Identifiers

PMID28600646
OpenAlexW2622248795

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.