Evidence map›Paper›PMID 28600529›Full record

ArticleScientific reports2017

Synthesis, Chemical Characterization and Multiscale Biological Evaluation of a Dimeric-cRGD Peptide for Targeted Imaging of α

Jamila Hedhli, Andrzej Czerwinski, Matthew Schuelke, Agata Płoska, Paweł Sowinski, Lukas La Hood, Spencer B Mamer, John A Cole, Paulina Czaplewska, Maciej Banach and 4 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

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  10. [Cells · 2020
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  12. Recent progress on micro- and nano-robots: towardsQuantitative imaging in medicine and surgery · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Jamila HedhliBeckman Institute for Advanced Science and Technology, Urbana, IL, USA.
Andrzej CzerwinskiPeptides International Inc., Louisville, KY, USA.
Matthew SchuelkeBeckman Institute for Advanced Science and Technology, Urbana, IL, USA.
Agata PłoskaBeckman Institute for Advanced Science and Technology, Urbana, IL, USA.
Paweł SowinskiNMR Laboratory, Faculty of Chemistry, Gdansk University of Technology, Gdansk, Poland.
Lukas La HoodBeckman Institute for Advanced Science and Technology, Urbana, IL, USA.
Spencer B MamerDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, USA.ORCID 0000-0002-5613-3596
John A ColeDepartment of Physics, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Paulina CzaplewskaIntercollegiate Faculty of Biotechnology of the University of Gdansk and Medical University of Gdansk, Gdansk, Poland.
Maciej BanachDepartment of Hypertension, Medical University of Lodz, Lodz, Poland.
Iwona T DobruckiBeckman Institute for Advanced Science and Technology, Urbana, IL, USA.
Leszek KalinowskiDepartment of Laboratory Diagnostics, Medical University of Gdansk, Gdansk, Poland.
Princess ImoukhuedeDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Lawrence W DobruckiBeckman Institute for Advanced Science and Technology, Urbana, IL, USA. dobrucki@illinois.edu.ORCID 0000-0002-6807-217X
University of Illinois Urbana-Champaign · USGdańsk Medical University · PLGdańsk University of Technology · PLMedical University of Lodz · PLPeptides International (United States) · US

Funding

Tissue microenvironment (TIMe) training programT32EB019944 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BHARGAVA, ROHIT, GASKINS, REX · 2016 to 2025
$1.9M
6 · The paper itself

Abstract

Cyclic peptides containing the Arg-Gly-Asp (RGD) sequence have been shown to specifically bind the angiogenesis biomarker α

Indexed as

AnimalsCell Line, TumorCopper RadioisotopesDimerizationHeterocyclic CompoundsHeterocyclic Compounds, 1-RingHumansHuman Umbilical Vein Endothelial CellsIntegrin alphaVbeta3KidneyMiceNeovascularization, PathologicOligopeptidesPeptides, CyclicPositron-Emission TomographyRats1,4,7-triazacyclononane-N,N',N''-triacetic acidarginyl-glycyl-aspartic acidCopper-64Copper Radioisotopescyclic arginine-glycine-aspartic acid peptideHeterocyclic CompoundsHeterocyclic Compounds, 1-RingIntegrin alphaVbeta3OligopeptidesPeptides, Cyclic

Identifiers

PMID28600529
PMCPMC5466598
OpenAlexW2621837941

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.